Autor segons l'article: Bladé C, Aragonès G, Arola-Arnal A, Muguerza B, Bravo FI, Salvadó MJ, Arola L, Suárez M.
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Aragonès Bargalló, Gerard / Arola Arnal, Anna / Arola Ferrer, Luis Maria / BLADÉ SEGARRA, MARIA CINTA / Bravo Vázquez, Francisca Isabel / Muguerza Marquínez, Maria Begoña / Salvadó Rovira, Maria Josepa / Suárez Recio, Manuel
Paraules clau: Polyphenols Molecular mechanisms Microbiota Metabolic diseases Flavonoids Circadian rhythms molecular mechanisms microbiota metabolic diseases flavonoids circadian rhythms
Resum: © 2016 International Union of Biochemistry and Molecular Biology. Proanthocyanidins (PAs) are the most abundant flavonoids in the human diet. Several epidemiological studies connect PA consumption and health benefits and the designation of PAs as healthy compounds started at the early stages of the 20th century. The beneficial health properties of PAs are attributed to their conjugated and colonic metabolites. Therefore, gut microbial compositions can determine the effectiveness of PAs. Reciprocally, dietary polyphenols can act as prebiotics. Recently, it has also been described that PAs modulate the circadian rhythm. Biochemical and epigenetic mechanisms, including the modulation of microRNAs, allow PAs to modulate cell functionality. PA effects in metabolic diseases are also reviewed.
Àrees temàtiques: Saúde coletiva Química Molecular medicine Medicine (miscellaneous) Medicina iii Medicina ii Medicina i Farmacia Enfermagem Endocrinology & metabolism Clinical biochemistry Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Biochemistry & molecular biology Biochemistry
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: gerard.aragones@urv.cat franciscaisabel.bravo@urv.cat begona.muguerza@urv.cat lluis.arola@urv.cat mariajosepa.salvado@urv.cat anna.arola@urv.cat manuel.suarez@urv.cat
Identificador de l'autor: 0000-0002-6468-3088 0000-0001-7384-8588 0000-0003-2767-1974 0000-0003-3883-3326 0000-0001-6529-1345 0000-0003-0122-8253
Data d'alta del registre: 2023-02-22
Versió de l'article dipositat: info:eu-repo/semantics/submittedVersion
Enllaç font original: https://iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.1249
URL Document de llicència: http://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Biofactors. 42 (1): 5-12
Referència de l'ítem segons les normes APA: Bladé C, Aragonès G, Arola-Arnal A, Muguerza B, Bravo FI, Salvadó MJ, Arola L, Suárez M. (2016). Proanthocyanidins in health and disease. Biofactors, 42(1), 5-12. DOI: 10.1002/biof.1249
DOI de l'article: 10.1002/biof.1249
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2016
Tipus de publicació: Journal Publications
Repositori URV