Articles producció científica> Bioquímica i Biotecnologia

Grape seed proanthocyanidins influence gut microbiota and enteroendocrine secretions in female rats

  • Dades identificatives

    Identificador: imarina:5131968
    Autors:
    Casanova-Marti, AngelaSerrano, JoanPortune, Kevin JSanz, YolandaTeresa Blay, MTerra, XimenaArdevol, AnnaPinent, Montserrat
    Resum:
    Grape seed proanthocyanidin extract (GSPE) modulates several parameters involved in metabolic syndrome. GSPE is a mixture of compounds, some which are rapidly absorbed, while others remain in the lumen where they might have effects that are translated to the whole organism. Our aim was to decipher if the 8-day treatment of GSPE, previously shown to reduce food intake, induces changes in the microbiota and enterohormone secretion. The ratio of Firmicutes?:?Bacteroidetes was lower in the microbiota of GSPE-treated rats compared to controls, and differences in several taxonomic families and genera were observed. Such modulation led to a reduction in cecal butyrate content. GSPE also increased plasma glucagon-like-peptide-1 (GLP-1). Gallic acid did not induce major changes in the microbiota profile nor in GLP-1 secretion. Correlations between several microbiota taxa and plasma triacylglycerol, adiposity, and enterohormones were observed. Modulation of microbiota may be one of the mechanism by which GSPE impacts metabolic health.
  • Altres:

    Autor segons l'article: Casanova-Marti, Angela; Serrano, Joan; Portune, Kevin J; Sanz, Yolanda; Teresa Blay, M; Terra, Ximena; Ardevol, Anna; Pinent, Montserrat
    Departament: Bioquímica i Biotecnologia
    Autor/s de la URV: Ardévol Grau, Anna / Blay Olivé, Maria Teresa / CASANOVA MARTÍ, ANGELA / Pinent Armengol, Montserrat / Terra Barbadora, Ximena
    Paraules clau: Rats, wistar Rats Proanthocyanidins Metabolic syndrome Humans Grape seed proanthocyanidins Grape seed extract Glucagon-like peptide 1 Gastrointestinal microbiome Gallic acid Female Butyrates Bacteria Animals Adiposity
    Resum: Grape seed proanthocyanidin extract (GSPE) modulates several parameters involved in metabolic syndrome. GSPE is a mixture of compounds, some which are rapidly absorbed, while others remain in the lumen where they might have effects that are translated to the whole organism. Our aim was to decipher if the 8-day treatment of GSPE, previously shown to reduce food intake, induces changes in the microbiota and enterohormone secretion. The ratio of Firmicutes?:?Bacteroidetes was lower in the microbiota of GSPE-treated rats compared to controls, and differences in several taxonomic families and genera were observed. Such modulation led to a reduction in cecal butyrate content. GSPE also increased plasma glucagon-like-peptide-1 (GLP-1). Gallic acid did not induce major changes in the microbiota profile nor in GLP-1 secretion. Correlations between several microbiota taxa and plasma triacylglycerol, adiposity, and enterohormones were observed. Modulation of microbiota may be one of the mechanism by which GSPE impacts metabolic health.
    Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biochemistry & molecular biology
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 29938270
    Adreça de correu electrònic de l'autor: anna.ardevol@urv.cat ximena.terra@urv.cat mteresa.blay@urv.cat montserrat.pinent@urv.cat
    Identificador de l'autor: 0000-0003-0156-7538 0000-0003-1043-5844 0000-0002-6256-9847 0000-0003-3550-5378
    Data d'alta del registre: 2024-10-19
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://pubs.rsc.org/en/content/articlelanding/2018/FO/C7FO02028G#!divAbstract
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Food & Function. 9 (3): 1672-1682
    Referència de l'ítem segons les normes APA: Casanova-Marti, Angela; Serrano, Joan; Portune, Kevin J; Sanz, Yolanda; Teresa Blay, M; Terra, Ximena; Ardevol, Anna; Pinent, Montserrat (2018). Grape seed proanthocyanidins influence gut microbiota and enteroendocrine secretions in female rats. Food & Function, 9(3), 1672-1682. DOI: 10.1039/c7fo02028g
    DOI de l'article: 10.1039/c7fo02028g
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2018
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Biochemistry & Molecular Biology,Food Science,Food Science & Technology,Medicine (Miscellaneous)
    Rats, wistar
    Rats
    Proanthocyanidins
    Metabolic syndrome
    Humans
    Grape seed proanthocyanidins
    Grape seed extract
    Glucagon-like peptide 1
    Gastrointestinal microbiome
    Gallic acid
    Female
    Butyrates
    Bacteria
    Animals
    Adiposity
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Odontología
    Nutrição
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Food science & technology
    Food science
    Farmacia
    Educação física
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
    Biochemistry & molecular biology
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