Autor segons l'article: IBARRECHE GUEREDIAGA, DAIANA; ARAGONÈS BARGALLÓ, GEMMA; Merino, Jordi; Kones, Richard; Ferre, Raimon; Plana, Nuria; Girona, Josefa; Aragones, Gemma; Ibarretxe, Daiana; Heras, Mercedes; Masana, Luis
Departament: Universitat Rovira i Virgili Oficina de Suport a la Recerca - Becaris Ciències Mèdiques Bàsiques Medicina i Cirurgia
Autor/s de la URV: ARAGONÈS BARGALLÓ, GEMMA / FERRÉ VALLÈS, RAIMON / Girona Tell, Josefa / HERAS IBAÑEZ, MERCEDES / Ibarretxe Gerediaga, Daiana / Masana Marín, Luis / MERINO RIBAS, JORDI / Plana Gil, Núria
Paraules clau: Abdominal obesity Adult Aged Cardiovascular risk Cohort studies Complications Cross-sectional relations Cross-sectional studies Diabetes mellitus, type 2 Diet therapy Disease Endothelial function Endothelium, vascular Etiology Female Health Humans Life-style changes Low-carbohydrate diets Male Markers Metabolic syndrome Metabolic syndrome x Middle aged Overweight Risk factors Self care Spain Type 2 diabetes mellitus Vascular function Very-low-carbohydrate Weight-loss
Resum: Low-carbohydrate diets have become increasingly popular for weight loss. Although they may improve some metabolic markers, particularly in type 2 diabetes mellitus (T2D) or the metabolic syndrome (MS), their net effect on arterial wall function remains unclear. The objective was to evaluate the relation between dietary macronutrient composition and the small artery reactive hyperaemia index (saRHI), a marker of small artery endothelial function, in a cohort of patients at increased cardiovascular (CV) risk. The present cross-sectional study included 247 patients. Diet was evaluated by a 3-d food-intake register and reduced to a novel low-carbohydrate diet score (LCDS). Physical examination, demographic, biochemical and anthropometry parameters were recorded, and the saRHI was measured in each patient. Individuals in the lowest LCDS quartile (Q1, 45 % carbohydrate; 20 % protein; 32 % fat) had higher saRHI values than those in the top quartile (Q4, 29 % carbohydrate, 24 % protein, 40 % fat; 1.66 (sd 0.41) v. 1.52 (sd 0.22), P= 0.037). These results were particularly strong in patients with the MS (Q1 = 1.82 (sd 0.32) v. Q4 = 1.61 (sd 027); P= 0.021) and T2D (Q1 = 1.78 (sd 0.31) v. Q4 = 1.62 (sd 0.35); P= 0.011). Multivariate analysis demonstrated that individuals in the highest LCDS quartile had a significantly negative coefficient of saRHI, which was independent of confounders (OR -0.85; 95 % CI 0.19, 0.92; P= 0.031). These findings suggest that a dietary pattern characterised by a low amount of carbohydrate, but high amounts of protein and fat, is associated with a poorer small artery vascular reactivity in patients with increased CV risk.
Àrees temàtiques: Administração pública e de empresas, ciências contábeis e turismo Biodiversidade Biotecnología Ciência de alimentos Ciências agrárias i Ciências ambientais Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Educação física Engenharias ii Engenharias iv Farmacia General medicine Interdisciplinar Matemática / probabilidade e estatística Medicina i Medicina ii Medicina iii Medicina veterinaria Medicine (miscellaneous) Nutrição Nutrition & dietetics Nutrition and dietetics Odontología Química Saúde coletiva Zootecnia / recursos pesqueiros
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: josefa.girona@urv.cat luis.masana@urv.cat nuria.plana@urv.cat josefa.girona@urv.cat daiana.ibarretxe@urv.cat
ISSN: 14752662
Identificador de l'autor: 0000-0002-6267-8779 0000-0002-0789-4954 0000-0002-4231-7618 0000-0002-6267-8779
Data d'alta del registre: 2023-02-26
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/negative-effect-of-a-lowcarbohydrate-highprotein-highfat-diet-on-small-peripheral-artery-reactivity-in-patients-with-increased-cardiovascular-risk/29A9DD30AC660BBDA5470D1E173C0E6F
Referència a l'article segons font original: British Journal Of Nutrition. 109 (7): 1241-1247
Referència de l'ítem segons les normes APA: IBARRECHE GUEREDIAGA, DAIANA; ARAGONÈS BARGALLÓ, GEMMA; Merino, Jordi; Kones, Richard; Ferre, Raimon; Plana, Nuria; Girona, Josefa; Aragones, Gemma; I (2013). Negative effect of a low-carbohydrate, high-protein, high-fat diet on small peripheral artery reactivity in patients with increased cardiovascular risk. British Journal Of Nutrition, 109(7), 1241-1247. DOI: 10.1017/S0007114512003091
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
DOI de l'article: 10.1017/S0007114512003091
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2013
Tipus de publicació: Journal Publications
Repositori URV