Autor segons l'article: Daura-Oller, Elias; Cabre, Maria; Montero, Miguel A.; Paternain, Jose L.; Romeu, Antoni;
Departament: Química Física i Inorgànica
Autor/s de la URV: Cabré Bargalló, Maria / DAURA OLLER, ELIES / Montero Simó, Miguel Angel / PATERNÁIN SUBERVIOLA, JOSÉ LUIS / ROMEU FIGUEROLA, ANTONIO RAMÓN
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Resum: In the present study, a positive training set of 30 known human imprinted gene coding regions are compared with a set of 72 randomly sampled human nonimprinted gene coding regions (negative training set) to identify genomic features common to human imprinted genes. The most important feature of the present work is its ability to use multivariate analysis to look at variation, at coding region DNA level, among imprinted and non-imprinted genes. There is a force affecting genomic parameters that appears through the use of the appropriate multivariate methods (principle components analysis (PCA) and quadratic discriminant analysis (QDA) to analyse quantitative genomic data. We show that variables, such as CG content, [bp]% CpG islands, [bp]% Large Tandem Repeats, and [bp]% Simple Repeats, are able to distinguish coding regions of human imprinted genes.
Àrees temàtiques: Molecular biology Medicina i Genetics & heredity Genetics Biotechnology & applied microbiology Biotechnology Biodiversidade Biochemistry & molecular biology
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1531-6912
Adreça de correu electrònic de l'autor: maria.cabre@urv.cat
Identificador de l'autor: 0000-0003-4124-8603
Data d'alta del registre: 2024-09-28
Volum de revista: 2009
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.hindawi.com/journals/ijg/2009/549387/
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Comparative And Functional Genomics. 2009 (549387): 549387-
Referència de l'ítem segons les normes APA: Daura-Oller, Elias; Cabre, Maria; Montero, Miguel A.; Paternain, Jose L.; Romeu, Antoni; (2009). A First-Stage Approximation to Identify New Imprinted Genes through Sequence Analysis of Its Coding Regions. Comparative And Functional Genomics, 2009(549387), 549387-. DOI: 10.1155/2009/549387
DOI de l'article: 10.1155/2009/549387
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2009
Tipus de publicació: Journal Publications