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Antimicrobial susceptibility, virulence potential and sequence types associated with Arcobacter strains recovered from human faeces

  • Dades identificatives

    Identificador: imarina:6389318
    Autors:
    Pérez-Cataluña ATapiol JBenavent CSarvise CGómez FMartínez BTerron-Puig MRecio GVilanova APujol IBallester FRezusta AFigueras M
    Resum:
    © 2017 The Authors. Purpose. The genus Arcobacter includes bacteria that are considered emergent pathogens because they can produce infections in humans and animals. The most common symptoms are bloody and non-bloody persistent diarrhea but cases with abdominal cramps without diarrhea or asymptomatic cases have also been described as well as cases with bacteremia. The objective was to characterize Arcobacter clinical strains isolated from the faeces of patients from three Spanish hospitals. Methodology. We have characterized 28 clinical strains (27 of A. butzleri and one of A. cryaerophilus) isolated from faeces, analysing their epidemiological relationship using the multilocus sequence typing (MLST) approach and screening them for their antibiotic susceptibility and for the presence of virulence genes. Results/Key findings. Typing results showed that only one of the 28 identified sequence types (i.e. ST 2) was already present in the MLST database. The other 27 STs constituted new records because they included new alleles for five of the seven genes or new combinations of known alleles of the seven genes. All strains were positive for the ciaB virulence gene and sensitive to tetracycline. However, 7.4% of the A. butzleri and A. cryaerophilus strains showed resistance to ciprofloxacin. Conclusion. The fact that epidemiological unrelated strains show the same ST indicates that other techniques with higher resolution should be developed to effectively recognize the infection source. Resistance to ciprofloxacin, one of the antibiotics recommended for the treatment of Arcobacter intestinal infections, demonstrated in 10.7% of the strains, indicates the importance of selecting the most appropriate effective treatment.
  • Altres:

    Autor segons l'article: Pérez-Cataluña A; Tapiol J; Benavent C; Sarvise C; Gómez F; Martínez B; Terron-Puig M; Recio G; Vilanova A; Pujol I; Ballester F; Rezusta A; Figueras M
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Figueras Salvat, María Josefa / Gomez Bertomeu, Frederic-Francesc / PÉREZ CATALUÑA, ALBA / Pujol Bajador, Isabel
    Paraules clau: Virulence genes Mlst Arcobacter cryaerophilus Arcobacter butzleri Antibiotic resistance mlst arcobacter cryaerophilus arcobacter butzleri antibiotic resistance
    Resum: © 2017 The Authors. Purpose. The genus Arcobacter includes bacteria that are considered emergent pathogens because they can produce infections in humans and animals. The most common symptoms are bloody and non-bloody persistent diarrhea but cases with abdominal cramps without diarrhea or asymptomatic cases have also been described as well as cases with bacteremia. The objective was to characterize Arcobacter clinical strains isolated from the faeces of patients from three Spanish hospitals. Methodology. We have characterized 28 clinical strains (27 of A. butzleri and one of A. cryaerophilus) isolated from faeces, analysing their epidemiological relationship using the multilocus sequence typing (MLST) approach and screening them for their antibiotic susceptibility and for the presence of virulence genes. Results/Key findings. Typing results showed that only one of the 28 identified sequence types (i.e. ST 2) was already present in the MLST database. The other 27 STs constituted new records because they included new alleles for five of the seven genes or new combinations of known alleles of the seven genes. All strains were positive for the ciaB virulence gene and sensitive to tetracycline. However, 7.4% of the A. butzleri and A. cryaerophilus strains showed resistance to ciprofloxacin. Conclusion. The fact that epidemiological unrelated strains show the same ST indicates that other techniques with higher resolution should be developed to effectively recognize the infection source. Resistance to ciprofloxacin, one of the antibiotics recommended for the treatment of Arcobacter intestinal infections, demonstrated in 10.7% of the strains, indicates the importance of selecting the most appropriate effective treatment.
    Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Nutrição Microbiology (medical) Microbiology Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias ii Engenharias i Educação física Educação Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: frederic-francesc.gomez@urv.cat isabel.pujol@urv.cat mariajose.figueras@urv.cat
    Identificador de l'autor: 0000-0002-8039-2889 0000-0002-2268-8980
    Data d'alta del registre: 2024-09-07
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.microbiologyresearch.org/content/journal/jmm/10.1099/jmm.0.000638
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Journal Of Medical Microbiology. 66 (12): 1736-1743
    Referència de l'ítem segons les normes APA: Pérez-Cataluña A; Tapiol J; Benavent C; Sarvise C; Gómez F; Martínez B; Terron-Puig M; Recio G; Vilanova A; Pujol I; Ballester F; Rezusta A; Figueras (2017). Antimicrobial susceptibility, virulence potential and sequence types associated with Arcobacter strains recovered from human faeces. Journal Of Medical Microbiology, 66(12), 1736-1743. DOI: 10.1099/jmm.0.000638
    DOI de l'article: 10.1099/jmm.0.000638
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2017
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Medicine (Miscellaneous),Microbiology,Microbiology (Medical)
    Virulence genes
    Mlst
    Arcobacter cryaerophilus
    Arcobacter butzleri
    Antibiotic resistance
    mlst
    arcobacter cryaerophilus
    arcobacter butzleri
    antibiotic resistance
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Odontología
    Nutrição
    Microbiology (medical)
    Microbiology
    Medicine (miscellaneous)
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    General medicine
    Farmacia
    Engenharias ii
    Engenharias i
    Educação física
    Educação
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Biotecnología
    Biodiversidade
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