Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-9-335
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Pallejà, Albert; D Harrington, Eoghan; Bork, Peer
DOI de l'article: 10.1186/1471-2164-9-335
Resum: Across the fully sequenced microbial genomes there are thousands of examples of overlapping genes. Many of these are only a few nucleotides long and are thought to function by permitting the coordinated regulation of gene expression. However, there should also be selective pressure against long overlaps, as the existence of overlapping reading frames increases the risk of deleterious mutations. Here we examine the longest overlaps and assess whether they are the product of special functional constraints or of erroneous annotation.
Any de publicació de la revista: 2008
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Data d'alta del registre: 2021-02-05
Volum de revista: 9
Repositori URV