Autor segons l'article: Hassan, Loay; Abdel-Nasser, Mohamed; Saleh, Adel; Omer, Osama A; Puig, Domenec
Departament: Enginyeria Informàtica i Matemàtiques
Autor/s de la URV: Abdelnasser Mohamed Mahmoud, Mohamed / Puig Valls, Domènec Savi
Paraules clau: Whole-slide imaging Nuclei segmentation Deep learning Choquet integral
Resum: Existing nuclei segmentation methods have obtained limited results with multi-center and multi-organ whole-slide images (WSIs) due to the use of different stains, scanners, overlapping, clumped nuclei, and the ambiguous boundary between adjacent cell nuclei. In an attempt to address these problems, we propose an efficient stain-aware nuclei segmentation method based on deep learning for multi-center WSIs. Unlike all related works that exploit a single-stain template from the dataset to normalize WSIs, we propose an efficient algorithm to select a set of stain templates based on stain clustering. Individual deep learning models are trained based on each stain template, and then, an aggregation function based on the Choquet integral is employed to combine the segmentation masks of the individual models. With a challenging multi-center multi-organ WSIs dataset, the experimental results demonstrate that the proposed method outperforms the state-of-art nuclei segmentation methods with aggregated Jaccard index (AJI) and F1-scores of 73.23% and 89.32%, respectively, while achieving a lower number of parameters.
Àrees temàtiques: Signal processing Physics, applied Hardware and architecture Engineering, electrical & electronic Engenharias iv Electrical and electronic engineering Control and systems engineering Computer science, information systems Computer networks and communications
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: mohamed.abdelnasser@urv.cat domenec.puig@urv.cat
Identificador de l'autor: 0000-0002-1074-2441 0000-0002-0562-4205
Data d'alta del registre: 2024-10-12
Volum de revista: 10
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.mdpi.com/2079-9292/10/8/954
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Electronics. 10 (8): 954-
Referència de l'ítem segons les normes APA: Hassan, Loay; Abdel-Nasser, Mohamed; Saleh, Adel; Omer, Osama A; Puig, Domenec (2021). Efficient Stain-Aware Nuclei Segmentation Deep Learning Framework for Multi-Center Histopathological Images. Electronics, 10(8), 954-. DOI: 10.3390/electronics10080954
DOI de l'article: 10.3390/electronics10080954
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2021
Tipus de publicació: Journal Publications