Articles producció científica> Ciències Mèdiques Bàsiques

A revision of malbranchea-like fungi from clinical specimens in the United States of America reveals unexpected novelty

  • Dades identificatives

    Identificador: imarina:9228583
    Autors:
    Rodriguez-Andrade, ErnestoCano-Lira, Jose F.Wiederhold, NathanPerez-Cantero, AlbaGuarro, JosepStchigel, Alberto M.
    Resum:
    The fungi of the order Onygenales can cause important human infections; however, their taxonomy and worldwide occurrence is still little known. We have studied and identified a representative number of clinical fungi belonging to that order from a reference laboratory in the USA. A total of 22 strains isolated from respiratory tract (40%) and human skin and nails (27.2%) showed a malbranchea-like morphology. Six genera were phenotypically and molecularly identified, i.e. Auxarthron/Malbranchea (68.2%), Arachnomyces (9.1%), Spiromastigoides (9.1%), and Currahmyces (4.5%), and two newly proposed genera (4.5% each). Based on the results of the phylogenetic study, we synonymized Auxarthron with Malbranchea, and erected two new genera: Pseudoarthropsis and Pseudomalbranchea. New species proposed are: Arachnomyces bostrychodes, A. graciliformis, Currahmyces sparsispora, Malbranchea gymnoascoides, M. multiseptata, M. stricta, Pseudoarthropsis crassispora, Pseudomalbranchea gemmata, and Spiromastigoides geomycoides, along with a new combination for Malbranchea gypsea. The echinocandins showed the highest in vitro antifungal activity against the studied isolates, followed by terbinafine and posaconazole; in contrast, amphotericin B, fluconazole, itraconazole and 5-fluorocytosine were less active or lacked in vitro activity against these fungi.
  • Altres:

    Autor segons l'article: Rodriguez-Andrade, Ernesto; Cano-Lira, Jose F.; Wiederhold, Nathan; Perez-Cantero, Alba; Guarro, Josep; Stchigel, Alberto M.;
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Cano Lira, José Francisco / Guarro Artigas, Josep / PÉREZ CANTERO, ALBA / Rodríguez Andrade, Ernesto / Stchigel Glikman, Alberto Miguel
    Paraules clau: Taxonomy Sp-nov. Phylogeny Onygenales Onychomycosis Onychocola-canadensis New taxa Nail Malbranchea Keratinophilic fungi Infection Genus Clinical fungi Auxarthron Arachnomycetales Antifungals
    Resum: The fungi of the order Onygenales can cause important human infections; however, their taxonomy and worldwide occurrence is still little known. We have studied and identified a representative number of clinical fungi belonging to that order from a reference laboratory in the USA. A total of 22 strains isolated from respiratory tract (40%) and human skin and nails (27.2%) showed a malbranchea-like morphology. Six genera were phenotypically and molecularly identified, i.e. Auxarthron/Malbranchea (68.2%), Arachnomyces (9.1%), Spiromastigoides (9.1%), and Currahmyces (4.5%), and two newly proposed genera (4.5% each). Based on the results of the phylogenetic study, we synonymized Auxarthron with Malbranchea, and erected two new genera: Pseudoarthropsis and Pseudomalbranchea. New species proposed are: Arachnomyces bostrychodes, A. graciliformis, Currahmyces sparsispora, Malbranchea gymnoascoides, M. multiseptata, M. stricta, Pseudoarthropsis crassispora, Pseudomalbranchea gemmata, and Spiromastigoides geomycoides, along with a new combination for Malbranchea gypsea. The echinocandins showed the highest in vitro antifungal activity against the studied isolates, followed by terbinafine and posaconazole; in contrast, amphotericin B, fluconazole, itraconazole and 5-fluorocytosine were less active or lacked in vitro activity against these fungi.
    Àrees temàtiques: Plant science Mycology Ecology, evolution, behavior and systematics Ciências biológicas iii Ciências biológicas i Ciências agrárias i Biodiversidade Agricultural and biological sciences (miscellaneous)
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: josep.guarro@urv.cat albertomiguel.stchigel@urv.cat jose.cano@urv.cat
    Identificador de l'autor: 0000-0002-7839-7568 0000-0003-3987-7996 0000-0003-4495-4394
    Data d'alta del registre: 2024-07-27
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://imafungus.biomedcentral.com/articles/10.1186/s43008-021-00075-x
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Ima Fungus. 12 (1):
    Referència de l'ítem segons les normes APA: Rodriguez-Andrade, Ernesto; Cano-Lira, Jose F.; Wiederhold, Nathan; Perez-Cantero, Alba; Guarro, Josep; Stchigel, Alberto M.; (2021). A revision of malbranchea-like fungi from clinical specimens in the United States of America reveals unexpected novelty. Ima Fungus, 12(1), -. DOI: 10.1186/s43008-021-00075-x
    DOI de l'article: 10.1186/s43008-021-00075-x
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2021
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Agricultural and Biological Sciences (Miscellaneous),Ecology, Evolution, Behavior and Systematics,Mycology,Plant Science
    Taxonomy
    Sp-nov.
    Phylogeny
    Onygenales
    Onychomycosis
    Onychocola-canadensis
    New taxa
    Nail
    Malbranchea
    Keratinophilic fungi
    Infection
    Genus
    Clinical fungi
    Auxarthron
    Arachnomycetales
    Antifungals
    Plant science
    Mycology
    Ecology, evolution, behavior and systematics
    Ciências biológicas iii
    Ciências biológicas i
    Ciências agrárias i
    Biodiversidade
    Agricultural and biological sciences (miscellaneous)
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