Repositori URV

Identificador: imarina:9245541

Handle: https://hdl.handle.net/20.500.11797/imarina9245541

Autors:
Tresserra-Rimbau ACastro-Barquero SBecerra-Tomás NBabio NMartínez-González MÁCorella DFitó MRomaguera DVioque JAlonso-Gomez AMWärnberg JMartínez JASerra-Majem LEstruch RTinahones FJLapetra JPintó XTur JALópez-Miranda JCano-Ibáñez NDelgado-Rodríguez MMatía-Martín PDaimiel LSánchez VMVidal JVázquez CRos EBasterra FJde la Puente MFAsensio EMCastañer OBullón-Vela VTojal-Sierra LGómez-Gracia ECases-Pérez EKonieczna JGarcía-Ríos ACasañas-Quintana TBernal-Lopez MRSantos-Lozano JMEsteve-Luque VBouzas CVázquez-Ruiz ZPalau-Galindo ABarragan RGrau MLRazquín CGoicolea-Güemez LToledo EVergaz MVLamuela-Raventós RMSalas-Salvadó J

Resum:
Previous studies suggested that dietary polyphenols could reduce the incidence and complications of type-2 diabetes (T2D); although the evidence is still limited and inconsistent. This work analyzes whether changing to a diet with a higher polyphenolic content is associated with an improved glucose profile. At baseline, and at 1 year of follow-up visits, 5921 participants (mean age 65.0 ± 4.9, 48.2% women) who had overweight/obesity and metabolic syndrome filled out a vali-dated 143-item semi-quantitative food frequency questionnaire (FFQ), from which polyphenol intakes were calculated. Energy-adjusted total polyphenols and subclasses were categorized in tertiles of changes. Linear mixed-effect models with random intercepts (the recruitment centers) were used to assess associations between changes in polyphenol subclasses intake and 1-year plasma glucose or glycosylated hemoglobin (HbA1c) levels. Increments in total polyphenol intake and some classes were inversely associated with better glucose levels and HbA1c after one year of follow-up. These associations were modified when the analyses were run considering diabetes status separately. To our knowledge, this is the first study to assess the relationship between changes in the intake of all polyphenolic groups and T2D-related parameters in a senior population with T2D or at high-risk of developing T2D.