Autor segons l'article: Hernandez, V; Angerud, A; Bogaert, E; Hussein, M; Lemire, M; García-Miguel, J; Saez, J
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Hernandez Masgrau, Victor
Paraules clau: Radiotherapy, intensity-modulated Radiotherapy planning, computer-assisted Radiotherapy dosage Radiometry Radiation-field offset Protocol Photon Phantoms, imaging Performance Particle accelerators Mlc
Resum: Background The Agility multileaf collimator (MLC) mounted in Elekta linear accelerators features some unique design characteristics, such as large leaf thickness, eccentric curvature at the leaf tip, and defocused leaf sides ('tilting'). These characteristics offer several advantages but modeling them in treatment planning systems (TPSs) is challenging. Purpose The goals of this study were to investigate the challenges faced when modeling the Agility in two commercial TPSs (Monaco and RayStation) and to explore how the implemented MLC models could be improved in the future. Methods Four linear accelerators equipped with the Agility, located at different centers, were used for the study. Three centers use the RayStation TPS and the other one uses Monaco. For comparison purposes, data from four Varian linear accelerators with the Millennium 120 MLC were also included. Average doses measured with asynchronous sweeping gap tests were used to characterize and compare the characteristics of the Millennium and the Agility MLCs and to assess the MLC model in the TPSs. The FOURL test included in the ExpressQA package, provided by Elekta, was also used to evaluate the tongue-and-groove with radiochromic films. Finally, raytracing was used to investigate the impact of the MLC geometry and to understand the results obtained for each MLC. Results The geometry of the Agility produces dosimetric effects associated with the rounded leaf end up to a distance 20 mm away from the leaf tip end measured at the isocenter plane. This affects the tongue-and-groove shadowing, which progressively increases along the distance to the tip end. The RayStation and Monaco TPSs did not account for this effect, which made trade-offs in the MLC parameters necessary and greatly varied the final MLC parameters used by different centers. Raytracing showed that these challenging leaf tip effects were directly related to the MLC geometry and that the characteristics mainly responsible for the large leaf tip effects of the Agility were its tilting design and its small source-to-collimator distance. Conclusions The MLC models implemented in RayStation and Monaco could not accurately reproduce the leaf tip effects for the Agility. Therefore, trade-offs are needed and the optimal MLC parameters are dependent on the specific characteristics of treatment plans. Refining the MLC models for the Agility to better approximate the measured leaf tip and tongue-and-groove effects would extend the validity of the MLC model, reduce the variability in the MLC parameters used by the community, and facilitate the standardization of the MLC configuration process.
Àrees temàtiques: Radiology, nuclear medicine and imaging Radiology, nuclear medicine & medical imaging Medicine (miscellaneous) Medicina ii Medicina i Interdisciplinar General medicine Engenharias iv Engenharias ii Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência da computação Biotecnología Biophysics Astronomia / física Antropologia / arqueologia
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: victor.hernandez@urv.cat
Identificador de l'autor: 0000-0003-3770-8486
Data d'alta del registre: 2024-09-07
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Medical Physics. 49 (12): 7404-7416
Referència de l'ítem segons les normes APA: Hernandez, V; Angerud, A; Bogaert, E; Hussein, M; Lemire, M; García-Miguel, J; Saez, J (2022). Challenges in modeling the Agility multileaf collimator in treatment planning systems and current needs for improvement. Medical Physics, 49(12), 7404-7416. DOI: 10.1002/mp.16016
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2022
Tipus de publicació: Journal Publications
Repositori URV