Autor segons l'article: Ruiz de Azua, Ma Josefina; Manocchio, Francesca; Cruz-Carrion, Alvaro; Arola-Arnal, Anna; Torres-Fuentes, Cristina; Adrian Bernal, Claudio; Sain, Juliana; Suarez, Manuel
Departament: Bioquímica i Biotecnologia
Autor/s de la URV: Arola Arnal, Anna / Cruz Carrión, Álvaro Javier / Manocchio, Francesca / Suárez Recio, Manuel / Torres Fuentes, Cristina
Paraules clau: Skeletal-muscle Seasonality Rats, inbred f344 Rats Photoperiod Muscle, skeletal Metabolism Liver Fatty acids, unsaturated Fatty acids Fatty acid profile Chrononutrition Animals seasonality rhythms physiology oxidation metabolism lipid-metabolism light fatty acid profile circadian clock cells
Resum: Circadian and seasonal variations produce variations in physiological processes throughout the day and the year, respectively. In this sense, both the light and the moment of feeding are strong modulators of the central and peripheral clocks. However, little is known about its influence on certain metabolic parameters and on the composition of liver and muscle fatty acids (FA). In the present study, 24 Fischer 344 rats were exposed for 11 weeks to different photoperiods, L6, L12 and L18, with 6, 12 and 18 h of light/day, respectively. They were fed a standard diet. Serum metabolic parameters, gene expression of liver enzymes and gastrocnemius muscle involved in the synthesis, elongation, desaturation and β-oxidation of FA were analyzed. We have found that exposure to different hours of light has a clear effect on FA composition and gene expression in the liver. Mainly, the biosynthesis of unsaturated FA was altered in the L18 animals with respect to those exposed to L12, while the L6 did not show significant changes. At the muscle level, differences were observed in the concentration of mono and polyunsaturated FA. A multivariate analysis confirmed the differences between L12 and L18 in a significant way. We conclude that exposure to long days produces changes in the composition of liver and muscle FA, as well as changes in the gene expression of oxidative enzymes compared to exposure to L12, which could be a consequence of different seasonal eating patterns.
Àrees temàtiques: Zootecnia / recursos pesqueiros Saúde coletiva Radiology, nuclear medicine and imaging Radiological and ultrasound technology Radiation Química Odontología Nutrição Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Farmacia Ensino Engenharias iv Engenharias iii Engenharias ii Engenharias i Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Biotecnología Biophysics Biodiversidade Biochemistry & molecular biology Astronomia / física
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: francesca.manocchio@urv.cat francesca.manocchio@urv.cat francesca.manocchio@urv.cat manuel.suarez@urv.cat anna.arola@urv.cat cristina.torres@urv.cat
Identificador de l'autor: 0000-0003-0122-8253 0000-0001-6529-1345 0000-0002-2917-6910
Data d'alta del registre: 2024-10-12
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.sciencedirect.com/science/article/pii/S1011134422002366
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Journal Of Photochemistry And Photobiology B-Biology. 238 112621-
Referència de l'ítem segons les normes APA: Ruiz de Azua, Ma Josefina; Manocchio, Francesca; Cruz-Carrion, Alvaro; Arola-Arnal, Anna; Torres-Fuentes, Cristina; Adrian Bernal, Claudio; Sain, Juli (2023). Fatty acid metabolism in liver and muscle is strongly modulated by photoperiod in Fischer 344 rats. Journal Of Photochemistry And Photobiology B-Biology, 238(), 112621-. DOI: 10.1016/j.jphotobiol.2022.112621
DOI de l'article: 10.1016/j.jphotobiol.2022.112621
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2023
Tipus de publicació: Journal Publications