Autor segons l'article: Miralles-Pérez B; Nogués MR; Sánchez-Martos V; Fortuño-Mar À; Ramos-Romero S; Torres JL; Ponomarenko J; Amézqueta S; Zhang X; Romeu M
Departament: Ciències Mèdiques Bàsiques
Autor/s de la URV: Miralles Pérez, Bernat / Nogués Llort, Maria Rosa / Romeu Ferran, Marta / Sánchez Martos, Vanessa
Paraules clau: Obesity Lipid peroxidation Insulin-resistance Insulin resistance Gut microbiota Glucose intolerance Fatty liver Endogenous antioxidants Dyslipidemia plasma lipid peroxidation insulin resistance induced obesity gut microbiota glucose intolerance glucose gene-expression fiber fatty liver endogenous antioxidants dyslipidemia catalase assay acid
Resum: The present study examined the influence of inulin on fecal microbiota, cardiometabolic risk factors, eicosanoids, and oxidative stress in rats on a high-fat (HF) diet. Thirty-six male Wistar–Kyoto rats were divided into three dietary groups: standard diet, HF diet, and HF diet + Inulin diet. After 10 weeks, the HF + Inulin diet promoted high dominance of a few bacterial genera including Blautia and Olsenella in feces while reducing richness, diversity, and rarity compared to the HF diet. These changes in fecal microbiota were accompanied by an increased amount of propionic acid in feces. The HF + Inulin diet decreased cardiometabolic risk factors, decreased the amount of the eicosanoids 11(12)-EET and 15-HETrE in the liver, and decreased oxidative stress in blood compared to the HF diet. In conclusion, increasing consumption of inulin may be a useful nutritional strategy to protect against the onset of obesity and its associated metabolic abnormalities by means of modulation of gut microbiota.
Àrees temàtiques: Plant science Microbiology Health professions (miscellaneous) Health (social science) Food science & technology Food science
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: bernat.miralles@urv.cat vanessa.sanchez@urv.cat mariarosa.nogues@urv.cat marta.romeu@urv.cat vanessa.sanchez@urv.cat bernat.miralles@urv.cat
Identificador de l'autor: 0000-0003-1294-7069 0000-0003-4626-5672 0000-0002-2131-1858 0000-0003-1294-7069
Data d'alta del registre: 2023-02-23
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.mdpi.com/2304-8158/11/24/4072
URL Document de llicència: http://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Foods. 11 (24):
Referència de l'ítem segons les normes APA: Miralles-Pérez B; Nogués MR; Sánchez-Martos V; Fortuño-Mar À; Ramos-Romero S; Torres JL; Ponomarenko J; Amézqueta S; Zhang X; Romeu M (2022). Influence of Dietary Inulin on Fecal Microbiota, Cardiometabolic Risk Factors, Eicosanoids, and Oxidative Stress in Rats Fed a High-Fat Diet. Foods, 11(24), -. DOI: 10.3390/foods11244072
DOI de l'article: 10.3390/foods11244072
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2022
Tipus de publicació: Journal Publications
Repositori URV