Articles producció científicaMedicina i Cirurgia

Clinical and Biomarker Profile Responses to Rehabilitation Treatment in Patients with Long COVID Characterized by Chronic Fatigue

  • Dades identificatives

    Identificador:  imarina:9326331
    Autors:  Binetti, Jessica; Real, Monica; Renzulli, Marcela; Bertran, Laia; Riesco, David; Perpinan, Carles; Mohedano, Alba; Segundo, Rosa San; Ortiz, Marta; Porras, Jose Antonio; Pineda, Daniela Rosanna; Auguet, Teresa
    Resum:
    Long COVID (LC) syndrome is a complex multiorgan symptom that persists beyond >12 weeks after SARS-CoV-2 infection. The most frequently associated symptom is fatigue. Physical activity and exercise are recommended, although specific studies are lacking. The objectives of the present work are to analyze the impact of a supervised exercise program on the clinical evolution of LC with fatigue patients and to identify whether certain circulating biomarkers could predict the response to rehabilitation. The rehabilitation treatment response was analyzed in 14 women diagnosed with LC and fatigue, based on the changes in the 6 min walk test and Borg/Fatigue Impact scales. Patients who showed improvement in the meters walked were considered responders to the therapy. A total of 65% of patients responded to the exercise program, with an improvement in the meters walked and in oxygen saturation, with stability in the percentage of meters walked. Participants with obesity and those double-vaccinated against SARS-CoV-2 presented a lower degree of fatigue. LC patients presented a favorable response to a supervised exercise program. Differences in creatinine and protein levels were observed between rehabilitation therapy responders and nonresponders. A good state of protein nutrition was related to a better rehabilitation response. The results are promising regarding possible predictive biomarkers of rehabilitation response, such as creatinine.
  • Altres:

    Enllaç font original: https://www.mdpi.com/1999-4915/15/7/1452
    Referència de l'ítem segons les normes APA: Binetti, Jessica; Real, Monica; Renzulli, Marcela; Bertran, Laia; Riesco, David; Perpinan, Carles; Mohedano, Alba; Segundo, Rosa San; Ortiz, Marta; Po (2023). Clinical and Biomarker Profile Responses to Rehabilitation Treatment in Patients with Long COVID Characterized by Chronic Fatigue. Viruses-Basel, 15(7), 1452-. DOI: 10.3390/v15071452
    Referència a l'article segons font original: Viruses-Basel. 15 (7): 1452-
    DOI de l'article: 10.3390/v15071452
    Any de publicació de la revista: 2023-07-01
    Entitat: Universitat Rovira i Virgili
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Data d'alta del registre: 2026-03-02
    Autor/s de la URV: Aguilar Crespillo, Carmen Isabel / Auguet Quintillà, Maria Teresa / Bertran Ramos, Laia / Binetti, Jessica Angela / Perpiñan Auguet, Carles / Porras Ledantes, Jose Antonio / Real Álvarez, Monica Maria / Riesco Acevedo, David Gerardo / San Segundo Mozo, Rosa María
    Departament: Medicina i Cirurgia
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Tipus de publicació: Journal Publications
    Autor segons l'article: Binetti, Jessica; Real, Monica; Renzulli, Marcela; Bertran, Laia; Riesco, David; Perpinan, Carles; Mohedano, Alba; Segundo, Rosa San; Ortiz, Marta; Porras, Jose Antonio; Pineda, Daniela Rosanna; Auguet, Teresa
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Àrees temàtiques: Zootecnia / recursos pesqueiros, Virology, Saúde coletiva, Química, Medicina veterinaria, Medicina ii, Medicina i, Interdisciplinar, Infectious diseases, Ciências biológicas iii, Ciências biológicas ii, Ciências biológicas i, Ciências ambientais, Ciências agrárias i, Biotecnología, Biodiversidade
    Adreça de correu electrònic de l'autor: davidgerardo.riesco@urv.cat, jessicaangela.binetti@urv.cat, carles.perpinan@urv.cat, joseantonio.porras@urv.cat, jessicaangela.binetti@urv.cat, jessicaangela.binetti@urv.cat, carles.perpinan@urv.cat, laia.bertranr@estudiants.urv.cat, laia.bertranr@estudiants.urv.cat, carmenisabel.aguilar@urv.cat, carmenisabel.aguilar@urv.cat, mariateresa.auguet@urv.cat, rosamaria.sansegundo@urv.cat
  • Paraules clau:

    Sars-cov-2
    Post-acute covid-19 syndrome
    Physical rehabilitation
    Long covid
    Humans
    Good health and well-being
    Female
    Fatigue syndrome
    chronic
    Creatinine
    Covid-19
    Chronic fatigue
    Biomarkers
    Infectious Diseases
    Virology
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Medicina veterinaria
    Medicina ii
    Medicina i
    Interdisciplinar
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Biotecnología
    Biodiversidade
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