Autor segons l'article: Binetti, Jessica; Real, Monica; Renzulli, Marcela; Bertran, Laia; Riesco, David; Perpinan, Carles; Mohedano, Alba; Segundo, Rosa San; Ortiz, Marta; Porras, Jose Antonio; Pineda, Daniela Rosanna; Auguet, Teresa
Departament: Medicina i Cirurgia
Autor/s de la URV: Auguet Quintillà, Maria Teresa / Bertran Ramos, Laia / Binetti, Jessica Angela / Perpiñan Auguet, Carles / Porras Ledantes, Jose Antonio / Real Álvarez, Monica Maria / Riesco Acevedo, David Gerardo / San Segundo Mozo, Rosa María
Paraules clau: Sars-cov-2 Post-acute covid-19 syndrome Physical rehabilitation Long covid Humans Female Fatigue syndrome, chronic Creatinine Covid-19 Chronic fatigue Biomarkers sars-cov-2 physical rehabilitation chronic fatigue biomarkers
Resum: Long COVID (LC) syndrome is a complex multiorgan symptom that persists beyond >12 weeks after SARS-CoV-2 infection. The most frequently associated symptom is fatigue. Physical activity and exercise are recommended, although specific studies are lacking. The objectives of the present work are to analyze the impact of a supervised exercise program on the clinical evolution of LC with fatigue patients and to identify whether certain circulating biomarkers could predict the response to rehabilitation. The rehabilitation treatment response was analyzed in 14 women diagnosed with LC and fatigue, based on the changes in the 6 min walk test and Borg/Fatigue Impact scales. Patients who showed improvement in the meters walked were considered responders to the therapy. A total of 65% of patients responded to the exercise program, with an improvement in the meters walked and in oxygen saturation, with stability in the percentage of meters walked. Participants with obesity and those double-vaccinated against SARS-CoV-2 presented a lower degree of fatigue. LC patients presented a favorable response to a supervised exercise program. Differences in creatinine and protein levels were observed between rehabilitation therapy responders and nonresponders. A good state of protein nutrition was related to a better rehabilitation response. The results are promising regarding possible predictive biomarkers of rehabilitation response, such as creatinine.
Àrees temàtiques: Zootecnia / recursos pesqueiros Virology Saúde coletiva Química Medicina veterinaria Medicina ii Medicina i Interdisciplinar Infectious diseases Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Biotecnología Biodiversidade
Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
Adreça de correu electrònic de l'autor: davidgerardo.riesco@urv.cat monicamaria.real@urv.cat jessicaangela.binetti@urv.cat carles.perpinan@urv.cat joseantonio.porras@urv.cat rosamaria.sansegundo@urv.cat jessicaangela.binetti@urv.cat carles.perpinan@urv.cat laia.bertranr@estudiants.urv.cat laia.bertranr@estudiants.urv.cat mariateresa.auguet@urv.cat
Identificador de l'autor: 0000-0001-6418-1822 0000-0001-7420-2914 0000-0001-9052-1368 0000-0001-9052-1368 0000-0003-0396-6428
Data d'alta del registre: 2024-09-21
Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
Enllaç font original: https://www.mdpi.com/1999-4915/15/7/1452
URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
Referència a l'article segons font original: Viruses-Basel. 15 (7): 1452-
Referència de l'ítem segons les normes APA: Binetti, Jessica; Real, Monica; Renzulli, Marcela; Bertran, Laia; Riesco, David; Perpinan, Carles; Mohedano, Alba; Segundo, Rosa San; Ortiz, Marta; Po (2023). Clinical and Biomarker Profile Responses to Rehabilitation Treatment in Patients with Long COVID Characterized by Chronic Fatigue. Viruses-Basel, 15(7), 1452-. DOI: 10.3390/v15071452
DOI de l'article: 10.3390/v15071452
Entitat: Universitat Rovira i Virgili
Any de publicació de la revista: 2023
Tipus de publicació: Journal Publications