Articles producció científica> Ciències Mèdiques Bàsiques

Improving the modelling of a multi-leaf collimator with tilted leaf sides used in radiotherapy

  • Dades identificatives

    Identificador: imarina:9366473
    Autors:
    Hussein, MAngerud, ASaez, JBogaert, ELemire, MBarry, MPatallo, ISShipley, DClark, CHHernandez, V
    Resum:
    Background and purpose: Multi-leaf collimators (MLCs) with tilted leaf sides have a complex transmission behaviour that is not easily matched by radiotherapy treatment planning systems (TPSs). We sought to develop an MLC model that can accurately match test fields and clinically relevant plans at different centres. Materials and methods: Two new MLC models were developed and evaluated within a research version of a commercial TPS. Prototype I used adjusted-constant transmissions and Prototype II used variable transmissions at the tongue-and-groove and leaf-tip regions. Three different centres evaluated these prototypes for a tilted MLC and compared them with their initial MLC model using test fields and patient-specific quality-assurance measurements of clinically relevant plans. For the latter, gamma passing rates (GPR) at 2 %/2mm were recorded. Results: For the prototypes the same set of MLC parameters could be used at all centres, with only a slight adjustment of the offset parameter. For centres A and C, average GPR were >95 % and within 0.5 % GPR difference between the standard, and prototype models. In center B, prototypes I and II improved the agreement in clinically relevant plans, with an increase in GPR of 2.3 % +/- 0.8 % and 3.0 +/- 0.8 %, respectively. Conclusions: The prototype MLC models were either similar or superior to the initial MLC model, and simpler to configure because fewer trade-offs were required. Prototype I performed comparably to the more sophisticated Prototype II and its configuration can be easily standardized, which can be useful to reduce variability and improve safety in clinical practice.
  • Altres:

    Autor segons l'article: Hussein, M; Angerud, A; Saez, J; Bogaert, E; Lemire, M; Barry, M; Patallo, IS; Shipley, D; Clark, CH; Hernandez, V
    Departament: Ciències Mèdiques Bàsiques
    Autor/s de la URV: Hernandez Masgrau, Victor
    Paraules clau: Tps modelling Tps commissioning System Mlc modelling Gap Calculation errors
    Resum: Background and purpose: Multi-leaf collimators (MLCs) with tilted leaf sides have a complex transmission behaviour that is not easily matched by radiotherapy treatment planning systems (TPSs). We sought to develop an MLC model that can accurately match test fields and clinically relevant plans at different centres. Materials and methods: Two new MLC models were developed and evaluated within a research version of a commercial TPS. Prototype I used adjusted-constant transmissions and Prototype II used variable transmissions at the tongue-and-groove and leaf-tip regions. Three different centres evaluated these prototypes for a tilted MLC and compared them with their initial MLC model using test fields and patient-specific quality-assurance measurements of clinically relevant plans. For the latter, gamma passing rates (GPR) at 2 %/2mm were recorded. Results: For the prototypes the same set of MLC parameters could be used at all centres, with only a slight adjustment of the offset parameter. For centres A and C, average GPR were >95 % and within 0.5 % GPR difference between the standard, and prototype models. In center B, prototypes I and II improved the agreement in clinically relevant plans, with an increase in GPR of 2.3 % +/- 0.8 % and 3.0 +/- 0.8 %, respectively. Conclusions: The prototype MLC models were either similar or superior to the initial MLC model, and simpler to configure because fewer trade-offs were required. Prototype I performed comparably to the more sophisticated Prototype II and its configuration can be easily standardized, which can be useful to reduce variability and improve safety in clinical practice.
    Àrees temàtiques: Radiology, nuclear medicine and imaging Radiology, nuclear medicine & medical imaging Radiation Oncology
    Accès a la llicència d'ús: https://creativecommons.org/licenses/by/3.0/es/
    Adreça de correu electrònic de l'autor: victor.hernandez@urv.cat
    Identificador de l'autor: 0000-0003-3770-8486
    Data d'alta del registre: 2024-08-03
    Versió de l'article dipositat: info:eu-repo/semantics/publishedVersion
    Enllaç font original: https://www.phiro.science/article/S2405-6316(24)00013-7/fulltext#%20
    URL Document de llicència: https://repositori.urv.cat/ca/proteccio-de-dades/
    Referència a l'article segons font original: Physics And Imaging In Radiation Oncology. 29 100543-
    Referència de l'ítem segons les normes APA: Hussein, M; Angerud, A; Saez, J; Bogaert, E; Lemire, M; Barry, M; Patallo, IS; Shipley, D; Clark, CH; Hernandez, V (2024). Improving the modelling of a multi-leaf collimator with tilted leaf sides used in radiotherapy. Physics And Imaging In Radiation Oncology, 29(), 100543-. DOI: 10.1016/j.phro.2024.100543
    DOI de l'article: 10.1016/j.phro.2024.100543
    Entitat: Universitat Rovira i Virgili
    Any de publicació de la revista: 2024
    Tipus de publicació: Journal Publications
  • Paraules clau:

    Oncology,Radiation,Radiology, Nuclear Medicine & Medical Imaging,Radiology, Nuclear Medicine and Imaging
    Tps modelling
    Tps commissioning
    System
    Mlc modelling
    Gap
    Calculation errors
    Radiology, nuclear medicine and imaging
    Radiology, nuclear medicine & medical imaging
    Radiation
    Oncology
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