Author, as appears in the article.: Montserrat Diéguez Pher G. Andersson Alexander Paptchkhine Maria Biosca Oscar Pàmies
Department: Química Física i Inorgànica
URV's Author/s: DIÉGUEZ FERNÁNDEZ, MONTSERRAT Pher G. Andersson Alexander Paptchkhine Maria Biosca PAMIES OLLÉ, OSCAR
Keywords: Asymmetric catalysis Hydrogenation
Abstract: This study identifies a series of Ir-bicyclic phosphoroamidite–oxazoline/thiazole catalytic systems that can hydrogenate a wide range of minimally functionalized olefins (including E- and Z-tri- and disubstituted substrates, vinylsilanes, enol phosphinates, tri- and disubstituted alkenylboronic esters, and a,b-unsaturated enones) in high enantioselectivities (ee values up to 99%) and conversions. The design of the new phosphoroamidite–oxazoline/thiazole ligands derives from a previous successful generation of bicyclic N-phosphane–oxazoline/thiazole ligands, by replacing the N-phosphane group with a p-acceptor biaryl phosphoroamidite moiety. A small but structurally important family of Ir-phosphoroamidite–oxazoline/thiazole precatalysts has thus been synthesized by changing the nature of the Ndonor group (either oxazoline or thiazole) and the configuration at the biaryl phosphoroamidite moiety. The substitution of the N-phosphane by a phosphoroamidite group in the bicyclic N- phosphane–oxazoline/thiazole ligands extended the range of olefins that can be successfully hydrogenated.
Research group: Organometàl.lics i Catàlisi Homogènia
Thematic Areas: Chemistry Química Química
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0947-6539
Author identifier: 0000-0002-8450-0656 n/a n/a n/a 0000-0002-2352-8508
Record's date: 2015-10-30
Last page: 3464
Journal volume: 21
Papper version: info:eu-repo/semantics/submittedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2015
First page: 3455
Publication Type: Pre-print
Repositori URV