Author, as appears in the article.: Miquel A. Pericàs Montserrat Diéguez Javier Mazuela Mercè Coll Erik A. Karlsson Xisco Caldentey Jèssica Margalef Oscar Pàmies
Department: Química Física i Inorgànica
URV's Author/s: Miquel A. Pericàs DIÉGUEZ FERNÁNDEZ, MONTSERRAT Javier Mazuela Mercè Coll Erik A. Karlsson Xisco Caldentey Jèssica Margalef PAMIES OLLÉ, OSCAR
Keywords: Asymmetric catalysis
Abstract: A library of modular iridium complexes derived from thioether-phosphite/phosphinite ligands has been evaluated in the asymmetric iridium-catalyzed hydrogenation of minimally functionalized olefins. The modular ligand design has been shown to be crucial in finding highly selective catalysts for each substrate. A DFT study of the transition state responsible for the enantiocontrol in the Ir-catalyzed hydrogenation is also described and used for further optimization of the crucial stereodefining moieties. Excellent enantioselectivities (enantiomeric excess (ee) values up to 99%) have been obtained for a range of substrates, including E- and Ztrisubstituted and disubstituted olefins, a,b-unsaturated enones, tri- and disubstituted alkenylboronic esters, and olefins with trifluoromethyl substituents.
Research group: Organometàl.lics i Catàlisi Homogènia
Thematic Areas: Chemistry Química Química
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0947-6539
Author identifier: 0000-0003-0195-8846 0000-0002-8450-0656 n/a n/a n/a n/a n/a 0000-0002-2352-8508
Record's date: 2015-11-26
Last page: 21214
Journal volume: 20
Papper version: info:eu-repo/semantics/acceptedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2014
First page: 21201
Publication Type: Post-print
Repositori URV