The effect of a hypocaloric diet on the short and long term control of morbid obesity

Identifier:  PC:1595

Handle: https://hdl.handle.net/20.500.11797/PC1595

Authors:  J Salas Salvado; S Blanch Miró; MA Recasens Garcia; R Solá Alberich

Abstract:
BACKGROUND: The ponderal evolution and biochemical parameters during the inpatient administration of a highly hypocaloric and high protein diet (VLCD) were evaluated. The efficacy at medium term of this treatment was determined and the possible determining factors of the ponderal evolution were analysed. METHODS: A VCLD was administered to 20 women with morbid obesity during 21 days. The modifications of the biochemical parameters were determined during admission. The ponderal evolution was studied during hospitalization and during 9 moths of outpatient follow up. The prognostic factors of ponderal evolution analysed were: age, attempts to lose weight, familiar history of obesity, maximum weight attained, weight and index of body mass (IMB) at study initiation and admission, loss of weight during admission and the number of outpatient controls. RESULTS: During hospitalization, a mean loss of 7,0 ± 1,9 kg, a significant decrease in glycaemia, cholesterol, triglycerides, lymphocytes and blood pressure were observed. It was found that ponderal loss at 3 and 6 months may be predicted by IBM upon initiation of the study. At 9 months weight was lower than at initiation of hospitalizatio but not than at discharge (p<0.001). Weight upon initiation of the study and the maximum reached explain that weight at 9 months in 82,5% of the cases. CONCLUSIONS: Highly hypocaloric and high protein diets lead to a significant weight loss which is maintained at medium term and an improvement in the factors of cardiovascular risk are observed. Of the factors evaluated, only the grade of obesity significantly influences ponderal evolution