Author, as appears in the article.: Jordi Salas-Salvado; Joan Fernandez-Ballart; Emilio Ros; Miguel Angel Martinez Gonzalez; Montserrat Fito; Ramon Estruch; Dolores Corella; Miquel Fiol; Enrique Gomez Gracia; Fernando Aros; Gemma Flores; Jose Lapetra; Rosa Lamuela Raventos; Valentina Ruiz Gutierrez; Mònica Bullo; Josep Basora; Maria Isabel Covas; the PREDIMED Study Investigators
Department: Bioquímica i Biotecnologia
URV's Author/s: SALAS SALVADÓ, JORGE; Joan Fernandez-Ballart; Emilio Ros; Miguel Angel Martinez Gonzalez; Montserrat Fito; Ramon Estruch; Dolores Corella; Miquel Fiol; Enrique Gomez Gracia; Fernando Aros; Gemma Flores; Jose Lapetra; Rosa Lamuela Raventos; Valentina Ruiz Gutierrez; BULLÓ BONET, MÒNICA; Josep Basora; Maria Isabel Covas; the PREDIMED Study Investigators
Keywords: Metabolic Syndrome Status PREDIMED study Randomized trial
Abstract: BACKGROUND:
Epidemiological studies suggest that the Mediterranean diet (MedDiet) may reduce the risk of developing the metabolic syndrome (MetS). We compared the 1-year effect of 2 behavioral interventions to implement the MedDiet vs advice on a low-fat diet on MetS status.
METHODS:
A total of 1224 participants were recruited from the PREDIMED (Prevención con Dieta Mediterránea) Study, a multicenter, 3-arm, randomized clinical trial to determine the efficacy of the MedDiet on the primary prevention of cardiovascular disease. Participants were older subjects at high risk for cardiovascular disease. Interventions were quarterly education about the MedDiet plus provision of either 1 L/wk of virgin olive oil (MedDiet + VOO) or 30 g/d of mixed nuts (MedDiet + nuts), and advice on a low-fat diet (control diet). All diets were ad libitum, and there was no increase in physical activity for any of the interventions. Lifestyle variables and MetS features as defined by the National Cholesterol Education Program Adult Treatment Panel III criteria were assessed.
RESULTS:
At baseline, 61.4% of participants met criteria for the MetS. One-year prevalence was reduced by 6.7%, 13.7%, and 2.0% in the MedDiet + VOO, MedDiet + nuts, and control diet groups, respectively (MedDiet + nuts vs control groups, P = .01; MedDiet + VOO vs control group, P = .18). Incident rates of the MetS were not significantly different among groups (22.9%, 17.9%, and 23.4%, respectively). After adjustment for sex, age, baseline obesity status, and weight changes, the odds ratios for reversion of MetS were 1.3 (95% confidence interval, 0.8-2.1) for the MedDiet + VOO group and 1.7 (1.1-2.6) for the MedDiet + nuts group compared with the control diet group.
CONCLUSION:
A traditional MedDiet enriched with nuts could be a useful tool in the management of the MetS.
Research group: Alimentació, Nutrició, Creixement i Salut Mental
Thematic Areas: Biochemistry and technology Bioquímica y tecnología Bioquímica i biotecnologia
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 0003-9926
Author identifier: N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D; N/D
Record's date: 2016-06-13
Last page: 2458
Journal volume: 168
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/773456
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Entity: Universitat Rovira i Virgili
Journal publication year: 2008
First page: 2449
Publication Type: Article Artículo Article
Repositori URV