Author, as appears in the article.: Vendrell, J. Vázquez, J.A. Valdés, S. Serrano-Rios, M. Rojo-Martínez, G. Pascual-Manich, G. Ortega, E. Mora-Peces, I. Menéndez, E. Martínez-Larrad, M.T. López-Alba, A. Gutiérrez, G. Gomis, R. Girbés, J. Gaztambide, S. Franch, J. Delgado, E. Catalá, M. Castell, C. Castaño, L. Casamitjana, R. Carmena, R. Bordiú, E. Bosch-Comas, A. Goday, A. Soriguer, F. Runkle, I. Fuentes, M. Calle-Pascual, A.L. Marcuello, C.
Papper version: info:eu-repo/semantics/publishedVersion
Department: Medicina i Cirurgia
e-ISSN: 1687-8345
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Abstract: Objective. To evaluate the association between diabetes mellitus and health-related quality of life (HRQOL) controlled for several sociodemographic and anthropometric variables, in a representative sample of the Spanish population. Methods. A population-based, cross-sectional, and cluster sampling study, with the entire Spanish population as the target population. Five thousand and forty-seven participants (2162/2885 men/women) answered the HRQOL short form 12-questionnaire (SF-12). The physical (PCS-12) and the mental component summary (MCS-12) scores were assessed. Subjects were divided into four groups according to carbohydrate metabolism status: normal, prediabetes, unknown diabetes (UNKDM), and known diabetes (KDM). Logistic regression analyses were conducted. Results. Mean PCS-12/MCS-12 values were /, respectively. Men had higher scores than women in both PCS-12 ( versus ; ) and MCS-12 ( versus ; ). Increasing age and obesity were associated with a poorer PCS-12 score. In women lower PCS-12 and MCS-12 scores were associated with a higher level of glucose metabolism abnormality (prediabetes and diabetes), ( for trend), but only the PCS-12 score was associated with altered glucose levels in men ( for trend). The Odds Ratio adjusted for age, body mass index (BMI) and educational level, for a PCS-12 score below the median was 1.62 (CI 95%: 1.2–2.19; ) for men with KDM and 1.75 for women with KDM (CI 95%: 1.26–2.43; ), respectively. Conclusion. Current study indicates that increasing levels of altered carbohydrate metabolism are accompanied by a trend towards decreasing quality of life, mainly in women, in a representative sample of Spanish population.
Entity: Universitat Rovira i Virgili.
Journal publication year: 2012
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1687-8337
Journal volume: 2012