A risk score to predict type 2 diabetes mellitus in an elderly Spanish Mediterranean population at high cardiovascular risk.

Identifier:  PC:222

Handle: https://hdl.handle.net/20.500.11797/PC222

Authors:  Guasch-Ferré, M.; Bulló, M.; Costa, B.; Martínez-Gonzalez, M.Á.; Ibarrola-Jurado, N.; Estruch, R.; Barrio, F.; Salas-Salvadó, J. PREDI-PLAN, Investigators (Babio N).

Abstract:
To develop and test a diabetes risk score to predict incident diabetes in an elderly Spanish Mediterranean population at high cardiovascular risk. A diabetes risk score was derived from a subset of 1381 nondiabetic individuals from three centres of the PREDIMED study (derivation sample). Multivariate Cox regression model ß-coefficients were used to weigh each risk factor. PREDIMED-personal Score included body-mass-index, smoking status, family history of type 2 diabetes, alcohol consumption and hypertension as categorical variables; PREDIMED-clinical Score included also high blood glucose. We tested the predictive capability of these scores in the DE-PLAN-CAT cohort (validation sample). The discrimination of Finnish Diabetes Risk Score (FINDRISC), German Diabetes Risk Score (GDRS) and our scores was assessed with the area under curve (AUC).