Author, as appears in the article.: Salas-Salvadó, J. for the PREDIMED Study Investigators. Sorli, J.V. Covas, M.I. Serra-Majem, L. Estruch, R. Ortega-Calvo, M. Salaverría, I. Wärnberg, J. Martínez-González, M.Á. Bulló, M. Ibarrola-Jurado, N. Babio, N.
Department: Bioquímica i Biotecnologia Ciències Mèdiques Bàsiques
URV's Author/s: Nancy Babio, Nuria ibarrola, Mónica Bulló, Miguel Ángel Martínez-González
Abstract: The Metabolic Syndrome (MetS) is a cluster of metabolic abnormalities that includes hyperglucemia, hypertension, dyslipidemia and central obesity, conferring an increased risk of cardiovascular disease. The white blood cell (WBC) count has been proposed as a marker for predicting cardiovascular risk. However, few prospective studies have evaluated the relationship between WBC subtypes and risk of MetS. Participants were recruited from seven PREDIMED study centers. Both a baseline cross-sectional (n = 4,377) and a prospective assessment (n = 1,637) were performed. Participants with MetS at baseline were excluded from the longitudinal analysis. The median follow-up was 3.9 years. Anthropometric measurements, blood pressure, fasting glucose, lipid profile and WBC counts were assessed at baseline and yearly during the follow-up. Participants were categorized by baseline WBC and its subtype count quartiles. Adjusted logistic regression models were fitted to assess the risk of MetS and its components.
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1932-6203
Journal volume: 8
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0058354
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1371/journal.pone.0058354
Entity: Universitat Rovira i Virgili.
Journal publication year: 2013
Repositori URV