Author, as appears in the article.: Mas, A.; Martí-Raga, M.; Peltier, E.; Beltran, G.; Marullo, P.
Department: Bioquímica i Biotecnologia
URV's Author/s: MAS BARON, ALBERTO; Martí-Raga, M.; Peltier, E.; BELTRAN CASELLAS, GEMMA; Marullo, P.
Keywords: Heterosis Saccharomyces cerevisiae
Abstract: Hybridization is known to improve complex traits due to heterosis and phenotypic robustness. However, these phenomena have been rarely explained at the molecular level. Here, the genetic determinism of Saccharomyces cerevisiae fermentation performance was investigated using a QTL mapping approach on an F1-progeny population. Three main QTL were detected, with positive alleles coming from both parental strains. The heterosis effect found in the hybrid was partially explained by three loci showing pseudooverdominance and dominance effects. The molecular dissection of those QTL revealed that the adaptation to second fermentation is related to pH, lipid, or osmotic regulation. Our results suggest that the stressful conditions of second fermentation have driven the selection of rare genetic variants adapted to maintain yeast cell homeostasis and, in particular, to low pH conditions.
Research group: Biotecnologia Enològica
Thematic Areas: Bioquímica i biotecnologia Bioquímica y tecnología Biochemistry and technology
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 2160-1836
Author identifier: n/a; n/a; n/a; 0000-0002-7071-205X; n/a
Record's date: 2017-03-06
Last page: 412
Journal volume: 7
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: http://www.g3journal.org/content/7/2/399
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: https://doi.org/10.1534/g3.116.037283
Entity: Universitat Rovira i Virgili
Journal publication year: 2017
First page: 399
Publication Type: Article Artículo Article
Repositori URV