Articles producció científica> Bioquímica i Biotecnologia

Polyphenol Levels Are Inversely Correlated with Body Weight and Obesity in an Elderly Population after 5 Years of Follow Up (The Randomised PREDIMED Study)

  • Identification data

    Identifier: PC:3290
    Authors:
    Salas-Salvadó, J.Guo, X.Tresserra-Rimbau, A.Estruch, R.Martínez-González, MA.Medina-Remón, A.Fitó, M.Corella, D.Portillo, MP.Moreno, JJ.Pi-Sunyer, X.Lamuela-Raventós, RM.
    Abstract:
    Overweight and obesity have been steadily increasing in recent years and currently represent a serious threat to public health. Few human studies have investigated the relationship between polyphenol intake and body weight. Our aim was to assess the relationship between urinary polyphenol levels and body weight. A cross-sectional study was performed with 573 participants from the PREDIMED (Prevención con Dieta Mediterránea) trial (ISRCTN35739639). Total polyphenol levels were measured by a reliable biomarker, total urinary polyphenol excretion (TPE), determined by the Folin-Ciocalteu method in urine samples. Participants were categorized into five groups according to their TPE at the fifth year. Multiple linear regression models were used to assess the relationships between TPE and obesity parameters; body weight (BW), body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR). After a five years follow up, significant inverse correlations were observed between TPE at the 5th year and BW (β = -1.004; 95% CI: -1.634 to -0.375, p = 0.002), BMI (β = -0.320; 95% CI: -0.541 to -0.098, p = 0.005), WC (β = -0.742; 95% CI: -1.326 to -0.158, p = 0.013), and WHtR (β = -0.408; 95% CI: -0.788 to -0.028, p = 0.036) after adjustments for potential confounders. To conclude, a greater polyphenol intake may thus contribute to reducing body weight in elderly people at high cardiovascular risk.
  • Others:

    Author, as appears in the article.: Salas-Salvadó, J.; Guo, X.; Tresserra-Rimbau, A.; Estruch, R.; Martínez-González, MA.; Medina-Remón, A.; Fitó, M.; Corella, D.; Portillo, MP.; Moreno, JJ.; Pi-Sunyer, X.; Lamuela-Raventós, RM.
    Department: Bioquímica i Biotecnologia
    URV's Author/s: SALAS SALVADÓ, JORGE; Guo, X.; Tresserra-Rimbau, A.; Estruch, R.; Martínez-González, MA.; Medina-Remón, A.; Fitó, M.; Corella, D.; Portillo, MP.; Moreno, JJ.; Pi-Sunyer, X.; Lamuela-Raventós, RM.
    Keywords: overweight obesity PREDIMED
    Abstract: Overweight and obesity have been steadily increasing in recent years and currently represent a serious threat to public health. Few human studies have investigated the relationship between polyphenol intake and body weight. Our aim was to assess the relationship between urinary polyphenol levels and body weight. A cross-sectional study was performed with 573 participants from the PREDIMED (Prevención con Dieta Mediterránea) trial (ISRCTN35739639). Total polyphenol levels were measured by a reliable biomarker, total urinary polyphenol excretion (TPE), determined by the Folin-Ciocalteu method in urine samples. Participants were categorized into five groups according to their TPE at the fifth year. Multiple linear regression models were used to assess the relationships between TPE and obesity parameters; body weight (BW), body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR). After a five years follow up, significant inverse correlations were observed between TPE at the 5th year and BW (β = -1.004; 95% CI: -1.634 to -0.375, p = 0.002), BMI (β = -0.320; 95% CI: -0.541 to -0.098, p = 0.005), WC (β = -0.742; 95% CI: -1.326 to -0.158, p = 0.013), and WHtR (β = -0.408; 95% CI: -0.788 to -0.028, p = 0.036) after adjustments for potential confounders. To conclude, a greater polyphenol intake may thus contribute to reducing body weight in elderly people at high cardiovascular risk.
    Research group: Alimentació, Nutrició, Creixement i Salut Mental
    Thematic Areas: Health sciences Ciencias de la salud Ciències de la salut
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 2072-6643
    Author identifier: 0000-0003-2700-7459; ; ; ; ; ; ; ; ; ; ;
    Record's date: 2018-06-26
    Last page: -
    Journal volume: 9
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/2072-6643/9/5/452
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.3390/nu9050452
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    First page: E452
    Publication Type: Article Artículo Article
  • Keywords:

    DIETOTERÀPIA
    NUTRICIÓ
    OBESITAT
    overweight
    obesity
    PREDIMED
    Health sciences
    Ciencias de la salud
    Ciències de la salut
    2072-6643
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