Articles producció científica> Bioquímica i Biotecnologia

Roles of proanthocyanidin rich extracts in obesity

  • Identification data

    Identifier: PC:3389
    Authors:
    Salvadó, MJ
    Abstract:
    Obesity is a multifactorial disorder involving an abnormal or excessive amount of body fat. Obese people have a very high probability of developing metabolic syndrome, a condition in which cholesterol, lipid, and glucose levels rise, causing diabetes and heart disease. From the point of view of energy balance, the main contributors to obesity are excessive energy intake, inadequate energy expenditure and metabolic malfunctions. For this reason, health organisations are working to implement policies and plans to promote healthy eating and active living. However, these measures have not yet proven sufficient to combat this worldwide epidemic; therefore, drugs and bioactive compounds are being investigated to complement the existing strategies. In the present review, we discuss the available data regarding the modulation of obesity by proanthocyanidin rich extracts. Because studies with human subjects are very scarce, we focus on studies using laboratory animals. The results of in vitro studies are included because, although they cannot be directly extrapolated to the biological effects of proanthocyanidin, they can reveal some mechanisms of action.
  • Others:

    Author, as appears in the article.: Salvadó, MJ
    Department: Bioquímica i Biotecnologia
    URV's Author/s: SALVADÓ ROVIRA, MARIA JOSEPA
    Abstract: Obesity is a multifactorial disorder involving an abnormal or excessive amount of body fat. Obese people have a very high probability of developing metabolic syndrome, a condition in which cholesterol, lipid, and glucose levels rise, causing diabetes and heart disease. From the point of view of energy balance, the main contributors to obesity are excessive energy intake, inadequate energy expenditure and metabolic malfunctions. For this reason, health organisations are working to implement policies and plans to promote healthy eating and active living. However, these measures have not yet proven sufficient to combat this worldwide epidemic; therefore, drugs and bioactive compounds are being investigated to complement the existing strategies. In the present review, we discuss the available data regarding the modulation of obesity by proanthocyanidin rich extracts. Because studies with human subjects are very scarce, we focus on studies using laboratory animals. The results of in vitro studies are included because, although they cannot be directly extrapolated to the biological effects of proanthocyanidin, they can reveal some mechanisms of action.
    Research group: Grup de Recerca en Nutrigenòmica
    Thematic Areas: Bioquímica i biotecnologia Bioquímica y tecnología Biochemistry and technology
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 2042-6496
    Author identifier: 0000-0003-3883-3326
    Record's date: 2019-01-17
    Last page: 1071
    Journal volume: 2015
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://pubs.rsc.org/en/content/articlelanding/2015/FO/C4FO01035C#!divAbstract
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1039/c4fo01035c
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2015
    First page: 1053
    Publication Type: Article Artículo Article
  • Keywords:

    Raïms--Ús terapèutic
    Proantocianidines
    Bioquímica i biotecnologia
    Bioquímica y tecnología
    Biochemistry and technology
    2042-6496
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