Author, as appears in the article.: López-Martínez, G. Rodríguez-Porrata, B. Margalef-Català, M. Cordero-Otero, R.
Department: Bioquímica i Biotecnologia
URV's Author/s: Gema López-Martínez, Boris Rodríguez-Porrata, Mar Margalef-Català, Ricardo Cordero-Otero
Abstract: The yeast Saccharomyces cerevisiae is able to overcome cell dehydration; cell metabolic activity is arrested during this period but restarts after rehydration. The yeast genes encoding hydrophilin proteins were characterised to determine their roles in the dehydration-resistant phenotype, and STF2p was found to be a hydrophilin that is essential for survival after the desiccation-rehydration process. Deletion of STF2 promotes the production of reactive oxygen species and apoptotic cell death during stress conditions, whereas the overexpression of STF2, whose gene product localises to the cytoplasm, results in a reduction in ROS production upon oxidative stress as the result of the antioxidant capacity of the STF2p protein.
Thematic Areas: Saccharomyces cerevisiae protein
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1932-6203
Journal volume: 7
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033324
Article's DOI: 10.1371/journal.pone.0033324
Entity: Universitat Rovira i Virgili.
Journal publication year: 2012
Repositori URV