Author, as appears in the article.: Eguaras, S; Toledo, E; Buil-Cosiales, P; Salas-Salvado, J; Corella, D; Gutierrez-Bedmar, M; Santos-Lozano, J M; Aros, F; Fiol, M; Fito, M; Ros, E; Serra-Majem, L; Pinto, X; Martinez, J A; Sorli, J V; Munoz, M A; Basora, J; Estruch, R; Martinez-Gonzalez, M A
Department: Medicina i Cirurgia Ciències Mèdiques Bàsiques Bioquímica i Biotecnologia
URV's Author/s: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Cabre Vila, Juan Jose / Fernández Ballart, Joan Domènech / Salas Salvadó, Jorge
Keywords: Waist-to-height ratio Waist to height ratio Waist circumference Treatment outcome Time factors Spain Risk factors Randomized controlled trial Protective factors Proportional hazards models Priority journal Primary prevention Physical activity Obesity, abdominal Non insulin dependent diabetes mellitus Multivariate analysis Multicenter study Middle aged Mediterranean diet Male Major clinical study Lifestyle Incidence Humans Human Heart infarction Follow up Female Dietary intervention Diet, mediterranean Demography Controlled study Cardiovascular risk Cardiovascular diseases Cardiovascular disease Body mass index Body mass Article Aged, 80 and over Aged Adult Adiposity Abdominal obesity mediterranean diet dietary intervention cardiovascular disease
Abstract: We tested the hypothesis that an intervention with a Mediterranean diet (MeDiet) could mitigate the well-known harmful effects of abdominal obesity on cardiovascular health.We assessed the relationship between baseline waist-to-height ratio (WHtR) and major cardiovascular events during a median follow-up of 4.8 years in the Prevention with Mediterranean Diet (PREDIMED) randomized primary prevention trial, which tested a MeDiet against a control diet (advice on a low-fat diet). We also examined whether the MeDiet intervention was able to counteract the detrimental cardiovascular effects of an increased WHtR. The trial included 7447 participants (55-80 years old, 57% women) at high cardiovascular risk but free of cardiovascular disease (CVD) at enrollment. An increased risk of CVD events (myocardial infarction, stroke, or cardiovascular death) was apparent for the highest versus the lowest quartile of WHtR (multivariable-adjusted hazard ratio: 1.98) (95% confidence interval: 1.10-3.57; linear trend: p = 0.019) only in the control-diet group, but not in the two groups allocated to intervention with MeDiet (p for interaction = 0.034). This apparent interaction suggesting that the intervention counterbalanced the detrimental cardiovascular effects of adiposity was also significant for body mass index (BMI) (p = 0.01) and waist circumference (p = 0.043).The MeDiet may counteract the harmful effects of increased adiposity on the risk of CVD.Copyright © 2015 Elsevier B.V. All rights reserved.
Thematic Areas: Serviço social Saúde coletiva Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Enfermagem Endocrinology, diabetes and metabolism Endocrinology & metabolism Educação física Ciências biológicas ii Ciências biológicas i Ciências ambientais Cardiology and cardiovascular medicine Cardiac & cardiovascular systems
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 15903729
Author's mail: juanjose.cabre@urv.cat josep.basora@urv.cat josep.basora@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
Author identifier: 0000-0003-1082-6861 0000-0003-2700-7459 0000-0003-3527-5277
Record's date: 2024-10-19
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.nmcd-journal.com/article/S0939-4753(15)00057-5/abstract
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrition Metabolism And Cardiovascular Diseases. 25 (6): 569-574
APA: Eguaras, S; Toledo, E; Buil-Cosiales, P; Salas-Salvado, J; Corella, D; Gutierrez-Bedmar, M; Santos-Lozano, J M; Aros, F; Fiol, M; Fito, M; Ros, E; Ser (2015). Does the Mediterranean diet counteract the adverse effects of abdominal adiposity?. Nutrition Metabolism And Cardiovascular Diseases, 25(6), 569-574. DOI: 10.1016/j.numecd.2015.03.001
Article's DOI: 10.1016/j.numecd.2015.03.001
Entity: Universitat Rovira i Virgili
Journal publication year: 2015
Publication Type: Journal Publications
Repositori URV