Author, as appears in the article.: Garcia-Arellano, Ana; Ramallal, Raul; Ruiz-Canela, Miguel; Salas-Salvado, Jordi; Corella, Dolores; Shivappa, Nitin; Schroeder, Helmut; Hebert, James R; Ros, Emilio; Gomez-Garcia, Enrique; Estruch, Ramon; Lapetra, Jose; Aros, Fernando; Fiol, Miquel; Serra-Majem, Lluis; Pinto, Xavier; Babio, Nancy; Gonzalez, Jose I; Fito, Montse; Alfredo Martinez, J; Martinez-Gonzalez, Miguel A
Department: Bioquímica i Biotecnologia Medicina i Cirurgia
e-ISSN: 2072-6643
URV's Author/s: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Cabre Vila, Juan Jose / Castro Salomó, Antoni / IBARROLA JURADO, NURIA / Salas Salvadó, Jorge / Solà Alberich, Rosa Maria
Keywords: Randomized controlled trial Prospective study Predimed study Predimed Outcome assessment Olive oil Nut Multicenter study Middle aged Mediterranean diet Male Low fat diet Inflammation Incidence Human High risk population Heart infarction Heart death Food frequency questionnaire Follow up Female Dietary inflammatory index Diet Cerebrovascular accident Cardiovascular risk Cardiovascular disease Assessment of humans Article Aged Adult predimed dietary inflammatory index cardiovascular disease
Abstract: Previous studies have reported an association between a more pro-inflammatory diet profile and various chronic metabolic diseases. The Dietary Inflammatory Index (DII) was used to assess the inflammatory potential of nutrients and foods in the context of a dietary pattern. We prospectively examined the association between the DII and the incidence of cardiovascular disease (CVD: myocardial infarction, stroke or cardiovascular death) in the PREDIMED (Prevención con Dieta Mediterránea) study including 7216 high-risk participants. The DII was computed based on a validated 137-item food frequency questionnaire. Multivariate-adjusted hazard ratios (HR) and 95% confidence intervals of CVD risk were computed across quartiles of the DII where the lowest (most anti-inflammatory) quartile is the referent. Risk increased across the quartiles (i.e., with increasing inflammatory potential): HR(quartile2) = 1.42 (95%CI = 0.97-2.09); HR(quartile3) = 1.85 (1.27-2.71); and HR(quartile4) = 1.73 (1.15-2.60). When fit as continuous the multiple-adjusted hazard ratio for each additional standard deviation of the DII was 1.22 (1.06-1.40). Our results provide direct prospective evidence that a pro-inflammatory diet is associated with a higher risk of cardiovascular clinical events.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20726643
Author's mail: juanjose.cabre@urv.cat josep.basora@urv.cat josep.basora@urv.cat antoni.castro@urv.cat jordi.salas@urv.cat rosa.sola@urv.cat nancy.babio@urv.cat
Author identifier: 0000-0003-1082-6861 0000-0001-5441-6333 0000-0003-2700-7459 0000-0002-8359-235X 0000-0003-3527-5277
Last page: 4138
Record's date: 2024-10-12
Journal volume: 7
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/7/6/4124
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 7 (6): 4124-4138
APA: Garcia-Arellano, Ana; Ramallal, Raul; Ruiz-Canela, Miguel; Salas-Salvado, Jordi; Corella, Dolores; Shivappa, Nitin; Schroeder, Helmut; Hebert, James R (2015). Dietary inflammatory index and incidence of cardiovascular disease in the PREDIMED study. Nutrients, 7(6), 4124-4138. DOI: 10.3390/nu7064124
Article's DOI: 10.3390/nu7064124
Entity: Universitat Rovira i Virgili
Journal publication year: 2015
First page: 4124
Publication Type: Journal Publications
Repositori URV