Author, as appears in the article.: Becerra-Tomas, Nerea; Diaz-Lopez, Andres; Rosique-Esteban, Nilria; Ros, Emilio; Buil-Cosiales, Pilar; Corella, Dolores; Estruch, Ramon; Fito, Montserrat; Serra-Majem, Lluis; Aros, Fernando; Maria Lamuela-Raventos, Rosa; Fiol, Miguel; Manuel Santos-Lozano, Jose; Diez-Espino, Javier; Portoles, Olga; Salas-Salvado, Jordi
Department: Bioquímica i Biotecnologia Medicina i Cirurgia
URV's Author/s: Babio Sánchez, Nancy Elvira / Basora Gallisa, Josep / Becerra Tomás, Nerea / Bulló Bonet, Mònica / Cabre Vila, Juan Jose / Castro Salomó, Antoni / Díaz López, Andres / IBARROLA JURADO, NURIA / ROSIQUE ESTEBAN, NÚRIA / Salas Huetos, Albert / Salas Salvadó, Jorge
Keywords: Type-2 diabetes Type 2 diabetes Risk factors Prospective studies Proportional hazards models Predimed-study Predimed study Middle aged Male Lentils Legumes Humans Glycemic index Follow-up studies Female Fabaceae Diet, mediterranean Diet Diabetes mellitus, type 2 Blood glucose Aged Adiposity predimed-study lentils legumes
Abstract: Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods.Prospective assessment of 3349 participants in the PREvención con DIeta MEDiterránea (PREDIMED) study without type 2 diabetes at baseline. Dietary information was assessed at baseline and yearly during follow-up. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) for type-2 diabetes incidence according to quartiles of cumulative average consumption of total legumes, lentils, chickpeas, dry beans and fresh peas.During a median follow-up of 4.3 years, 266 new cases of type 2 diabetes occurred. Individuals in the highest quartile of total legume and lentil consumption had a lower risk of diabetes than those in the lowest quartile (HR: 0.65; 95% CI: 0.43, 0.96; P-trend = 0.04; and HR: 0.67; 95% CI: 0.46-0.98; P-trend = 0.05, respectively). A borderline significant association was also observed for chickpeas consumption (HR 0.68; 95% CI: 0.46, 1.00; P-trend = 0.06). Substitutions of half a serving/day of legumes for similar servings of eggs, bread, rice or baked potato was associated with lower risk of diabetes incidence.A frequent consumption of legumes, particularly lentils, in the context of a Mediterranean diet, may provide benefits on type 2 diabetes prevention in older adults at high cardiovascular risk.The trial is registered at http://www.controlled-trials.com (ISRCTN35739639). Registration date: 5th October 2005.Copyright © 2017 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
Thematic Areas: Saúde coletiva Química Odontología Nutrition and dietetics Nutrition & dietetics Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias iv Enfermagem Educação física Critical care and intensive care medicine Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 02615614
Author's mail: juanjose.cabre@urv.cat josep.basora@urv.cat andres.diaz@urv.cat albert.salas@urv.cat nerea.becerra@urv.cat monica.bullo@urv.cat josep.basora@urv.cat antoni.castro@urv.cat jordi.salas@urv.cat nancy.babio@urv.cat
Author identifier: 0000-0003-1082-6861 0000-0002-7500-5629 0000-0001-5914-6862 0000-0002-4429-6507 0000-0002-0218-7046 0000-0001-5441-6333 0000-0003-2700-7459 0000-0003-3527-5277
Record's date: 2024-10-12
Papper version: info:eu-repo/semantics/acceptedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Clinical Nutrition. 37 (3): 906-913
APA: Becerra-Tomas, Nerea; Diaz-Lopez, Andres; Rosique-Esteban, Nilria; Ros, Emilio; Buil-Cosiales, Pilar; Corella, Dolores; Estruch, Ramon; Fito, Montserr (2018). Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study.. Clinical Nutrition, 37(3), 906-913. DOI: 10.1016/j.clnu.2017.03.015
Entity: Universitat Rovira i Virgili
Journal publication year: 2018
Publication Type: Journal Publications
Repositori URV