Author, as appears in the article.: Guo X, Tresserra-Rimbau A, Estruch R, Martínez-González MA, Medina-Remón A, Fitó M, Corella D, Salas-Salvadó J, Portillo MP, Moreno JJ, Pi-Sunyer X, Lamuela-Raventós RM
Department: Bioquímica i Biotecnologia
e-ISSN: 2072-6643
URV's Author/s: Salas Salvadó, Jorge
Keywords: Obesity Overweight Polyphenol Polyphenols Predimed Urine
Abstract: Overweight and obesity have been steadily increasing in recent years and currently represent a serious threat to public health. Few human studies have investigated the relationship between polyphenol intake and body weight. Our aim was to assess the relationship between urinary polyphenol levels and body weight. A cross-sectional study was performed with 573 participants from the PREDIMED (Prevención con Dieta Mediterránea) trial (ISRCTN35739639). Total polyphenol levels were measured by a reliable biomarker, total urinary polyphenol excretion (TPE), determined by the Folin-Ciocalteu method in urine samples. Participants were categorized into five groups according to their TPE at the fifth year. Multiple linear regression models were used to assess the relationships between TPE and obesity parameters; body weight (BW), body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR). After a five years follow up, significant inverse correlations were observed between TPE at the 5th year and BW (? = -1.004; 95% CI: -1.634 to -0.375, p = 0.002), BMI (? = -0.320; 95% CI: -0.541 to -0.098, p = 0.005), WC (? = -0.742; 95% CI: -1.326 to -0.158, p = 0.013), and WHtR (? = -0.408; 95% CI: -0.788 to -0.028, p = 0.036) after adjustments for potential confounders. To conclude, a greater polyphenol intake may thus contribute to reducing body weight in elderly people at high cardiovascular risk.
Thematic Areas: Biotecnología Ciência de alimentos Ciências agrárias i Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Economia Educação física Enfermagem Engenharias ii Engenharias iv Farmacia Food science Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Nutrição Nutrition & dietetics Nutrition and dietetics Planejamento urbano e regional / demografia Psicología Química Saúde coletiva Zootecnia / recursos pesqueiros
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jordi.salas@urv.cat
ISSN: 20726643
Author identifier: 0000-0003-2700-7459
Record's date: 2023-02-18
Journal volume: 9
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/9/5/452
Papper original source: Nutrients. 9 (5): E452-
APA: Guo X, Tresserra-Rimbau A, Estruch R, Martínez-González MA, Medina-Remón A, Fitó M, Corella D, Salas-Salvadó J, Portillo MP, Moreno JJ, Pi-Sunyer X, L (2017). Polyphenol Levels Are Inversely Correlated with Body Weight and Obesity in an Elderly Population after 5 Years of Follow Up (The Randomised PREDIMED Study).. Nutrients, 9(5), E452-. DOI: 10.3390/nu9050452
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.3390/nu9050452
Entity: Universitat Rovira i Virgili
Journal publication year: 2017
Publication Type: Journal Publications
Repositori URV