Articles producció científicaQuímica Analítica i Química Orgànica

Functional-Group-Tolerant

  • Identification data

    Identifier:  imarina:3654708
    Handle: https://hdl.handle.net/20.500.11797/imarina3654708
    Authors:  Maestre, Lourdes; Dorel, Ruth; Pablo, Oscar; Escofet, Imma; Sameera, W M C; Alvarez, Eleuterio; Maseras, Feliu; Mar Diaz-Requejo, M; Echavarren, Antonio M; Perez, Pedro J
    Abstract:
    Silver(I) promotes the highly chemoselective N-amidation of tertiary amines under catalytic conditions to form aminimides by nitrene transfer from PhI¿NTs. Remarkably, this transformation proceeds in a selective manner in the presence of olefins and other functional groups without formation of the commonly observed aziridines or C-H insertion products. The methodology can be applied not only to rather simple tertiary amines but also to complex natural molecules such as brucine or quinine, where the products derived from N-N bond formation were exclusively formed. Theoretical mechanistic studies have shown that this selective N-amidation reaction proceeds through triplet silver nitrenes.

  • Others:

    Link to the original source: https://pubs.acs.org/doi/abs/10.1021/jacs.6b08219
    APA: Maestre, Lourdes; Dorel, Ruth; Pablo, Oscar; Escofet, Imma; Sameera, W M C; Alvarez, Eleuterio; Maseras, Feliu; Mar Diaz-Requejo, M; Echavarren, Anton (2017). Functional-Group-Tolerant, Silver-Catalyzed N-N Bond Formation by Nitrene Transfer to Amines. Journal Of The American Chemical Society, 139(6), 2216-2223. DOI: 10.1021/jacs.6b08219
    Paper original source: Journal Of The American Chemical Society. 139 (6): 2216-2223
    Article's DOI: 10.1021/jacs.6b08219
    Journal publication year: 2017
    Entity: Universitat Rovira i Virgili
    Paper version: info:eu-repo/semantics/publishedVersion
    Record's date: 2025-02-19
    URV's Author/s: ECHAVARREN PABLOS, ANTONIO
    Department: Química Analítica i Química Orgànica
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Journal Publications
    Author, as appears in the article.: Maestre, Lourdes; Dorel, Ruth; Pablo, Oscar; Escofet, Imma; Sameera, W M C; Alvarez, Eleuterio; Maseras, Feliu; Mar Diaz-Requejo, M; Echavarren, Antonio M; Perez, Pedro J
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Thematic Areas: Química, Materiais, Interdisciplinar, General chemistry, Farmacia, Engenharias iv, Engenharias iii, Engenharias ii, Colloid and surface chemistry, Ciências biológicas ii, Ciências biológicas i, Ciências agrárias i, Ciência de alimentos, Chemistry, multidisciplinary, Chemistry (miscellaneous), Chemistry (all), Chemistry, Catalysis, Biochemistry, Astronomia / física
    Author's mail: antoniomaria.echavarren@urv.cat

  • Keywords:

    Silver
    Bond formation
    Amines
    Biochemistry
    Catalysis
    Chemistry
    Chemistry (Miscellaneous)
    Multidisciplinary
    Colloid and Surface Chemistry
    Química
    Materiais
    Interdisciplinar
    General chemistry
    Farmacia
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Chemistry (all)
    Astronomia / física

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