Author, as appears in the article.: Fernández-Castillejo S, Valls RM, Castañer O, Rubió L, Catalán Ú, Pedret A, Macià A, Sampson ML, Covas MI, Fitó M, Motilva MJ, Remaley AT, Solà R.
Department: Medicina i Cirurgia
URV's Author/s: Catalán Santos, Úrsula / FERNÁNDEZ CASTILLEJO, SARA / Pedret Figuerola, Anna / Solà Alberich, Rosa Maria / Valls Zamora, Rosa Maria
Keywords: Virgin olive oil Thyme Polyphenols Olive oil Lipoprotein subclasses Ldl-p/hdl-p ratio Hdl-c/hdl-p ratio Hdl-c/hdl-p and ldl-p/hdl-p ratios polyphenols olive oil lipoprotein subclasses hdl-c/hdl-p and ldl-p/hdl-p ratios
Abstract: SCOPE: Lipoprotein particle measures performed by nuclear magnetic resonance (NMR), and associated ratios, may be better markers for atherosclerosis risk than conventional lipid measures. The effect of two functional olive oils, one enriched with its polyphenols (FVOO, 500 ppm), and the other (FVOOT) with them (250 ppm) and those of thyme (250 ppm), versus an standard virgin olive oil (VOO), on lipoprotein particle atherogenic ratios and subclasses profiles was assessed. METHODS AND RESULTS: In a randomized, double-blind, crossover, controlled trial, 33 hypercholesterolemic individuals received 25 mL/day of VOO, FVOO, and FVOOT. Intervention periods were of 3-weeks separated by 2-week washout periods. Lipoprotein particle counts and subclasses were measured by NMR. Polyphenols from olive oil and thyme modified the lipoprotein subclasses profile and decreased the LDL-P/total HDL particle (HDL-P), small HDL/large HDL, and HDL-cholesterol/HDL-P ratios, and decreased the lipoprotein insulin resistance index (LP-IR) (P<0.05). CONCLUSIONS: Olive oil polyphenols, and those from thyme provided benefits on lipoprotein particle atherogenic ratios and subclasses profile distribution. Polyphenol-enriched olive oil is a way of increasing the olive oil healthy properties while consuming the same amount of fat, as well as a useful and complementary tool for the management of cardiovascular risk individuals.
Thematic Areas: Agricultural sciences
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: ursula.catalan@urv.cat anna.pedret@urv.cat rosa.sola@urv.cat rosamaria.valls@urv.cat
Author identifier: 0000-0001-8884-9823 0000-0002-5327-932X 0000-0002-8359-235X 0000-0002-3351-0942
Record's date: 2023-11-11
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/10.1002/mnfr.201501068
Papper original source: Molecular Nutrition & Food Research. 60 (7): 1544-1554
APA: Fernández-Castillejo S, Valls RM, Castañer O, Rubió L, Catalán Ú, Pedret A, Macià A, Sampson ML, Covas MI, Fitó M, Motilva MJ, Remaley AT, Solà R. (2016). Polyphenol rich olive oils improve lipoprotein particle atherogenic ratios and subclasses profile: A randomized, crossover, controlled trial. Molecular Nutrition & Food Research, 60(7), 1544-1554. DOI: 10.1002/mnfr.201501068
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1002/mnfr.201501068
Entity: Universitat Rovira i Virgili
Journal publication year: 2016
Publication Type: Journal Publications