Articles producció científica> Química Física i Inorgànica

Extending the Substrate Scope in the Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with Ir-P Stereogenic Aminophosphine-Oxazoline Catalysts

  • Identification data

    Identifier: imarina:4859715
    Handle: https://hdl.handle.net/20.500.11797/imarina4859715
    Authors:
    Biosca M, Salomó E, de la Cruz-Sánchez P, Riera A, Verdaguer X, Pàmies O, Diéguez M
    Abstract:
    Air-stable and readily available Ir-catalyst precursors modified with MaxPHOX-type ligands have been successfully applied in the challenging asymmetric hydrogenation of tetrasubstituted olefins under mild reaction conditions. Gratifyingly, these catalyst precursors are able to efficiently hydrogenate not only a range of indene derivatives (ee's up to 96%) but also 1,2-dihydronapthalene derivatives and acyclic olefins (ee's up to 99%), which both constitute the most challenging substrates for this transformation.

  • Others:

    Author, as appears in the article.: Biosca M, Salomó E, de la Cruz-Sánchez P, Riera A, Verdaguer X, Pàmies O, Diéguez M
    Department: Química Física i Inorgànica
    URV's Author/s: Biosca Brull, Maria / De La Cruz Sánchez Badia, Pol / Diéguez Fernández, Montserrat / Pamies Ollé, Oscar
    Keywords: Phosphorus ligands Asymmetric hydrogenation
    Abstract: Air-stable and readily available Ir-catalyst precursors modified with MaxPHOX-type ligands have been successfully applied in the challenging asymmetric hydrogenation of tetrasubstituted olefins under mild reaction conditions. Gratifyingly, these catalyst precursors are able to efficiently hydrogenate not only a range of indene derivatives (ee's up to 96%) but also 1,2-dihydronapthalene derivatives and acyclic olefins (ee's up to 99%), which both constitute the most challenging substrates for this transformation.
    Thematic Areas: Química Physical and theoretical chemistry Organic chemistry Medicina ii Medicina i Materiais Interdisciplinar General medicine Farmacia Ciências biológicas ii Ciências biológicas i Ciências agrárias i Chemistry, organic Biotecnología Biodiversidade Biochemistry
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 15237060
    Author's mail: maria.biosca@urv.cat pol.delacruzsanchez@estudiants.urv.cat pol.delacruzsanchez@estudiants.urv.cat oscar.pamies@urv.cat montserrat.dieguez@urv.cat
    Author identifier: 0000-0002-9116-6318 0000-0002-2352-8508 0000-0002-8450-0656
    Last page: 811
    Record's date: 2024-07-13
    Journal volume: 21
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.8b04084
    Papper original source: Organic Letters. 21 (3): 807-811
    APA: Biosca M, Salomó E, de la Cruz-Sánchez P, Riera A, Verdaguer X, Pàmies O, Diéguez M (2019). Extending the Substrate Scope in the Hydrogenation of Unfunctionalized Tetrasubstituted Olefins with Ir-P Stereogenic Aminophosphine-Oxazoline Catalysts. Organic Letters, 21(3), 807-811. DOI: 10.1021/acs.orglett.8b04084
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1021/acs.orglett.8b04084
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2019
    First page: 807
    Publication Type: Journal Publications

  • Keywords:

    Biochemistry,Chemistry, Organic,Organic Chemistry,Physical and Theoretical Chemistry
    Phosphorus ligands
    Asymmetric hydrogenation
    Química
    Physical and theoretical chemistry
    Organic chemistry
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    General medicine
    Farmacia
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Chemistry, organic
    Biotecnología
    Biodiversidade
    Biochemistry

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