Author, as appears in the article.: Bazal P; Gea A; Martínez-González MA; Salas-Salvadó J; Asensio EM; Muñoz-Bravo C; Fiol M; Muñoz MA; Lapetra J; Serra-Majem LL; Pintó X; González JI; Becerra-Tomás N; Fitó M; Ros E; Alonso-Gómez A; Ruiz-Canela M
Department: Bioquímica i Biotecnologia
URV's Author/s: Becerra Tomás, Nerea / Salas Salvadó, Jorge
Keywords: Adult Adverse event Aged Aged, 80 and over Alcohol Alcohol consumption Alcohol drinking Antioxidant Article Atrial fibrillation Body mass Cardiovascular risk Clinical trial Depression Diet, mediterranean Drinking behavior Electrocardiogram Feeding behavior Female Follow up Food frequency questionnaire Hazard ratio Heart disease Human Humans Hypertension Incidence Major clinical study Male Mediterranean Mediterranean diet Middle aged Multicenter study Physical activity Priority journal Prognosis Prospective studies Prospective study Red wine Risk assessment Risk factor Risk factors Self report Spain Time factor Time factors Very elderly Wine
Abstract: © 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University Background and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP)(10–30 g/d in men and 5–15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR)with 95% confidence intervals (95% CI)of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67–1.37), adherents to MADP (HR: 1.15 95%CI: 0.75–1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53–1.58), compared with non-drinkers. Conclusions: In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption)was not associated with an increased incidence of AF. Clinical trials: URL: http://www.controlled-trials.com. Unique identifier: ISRCTN35739639.
Thematic Areas: Cardiac & cardiovascular systems Cardiology and cardiovascular medicine Ciências ambientais Ciências biológicas i Ciências biológicas ii Educação física Endocrinology & metabolism Endocrinology, diabetes and metabolism Enfermagem Farmacia General medicine Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Medicine (miscellaneous) Nutrição Nutrition & dietetics Nutrition and dietetics Saúde coletiva Serviço social
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jordi.salas@urv.cat nerea.becerra@urv.cat
ISSN: 15903729
Author identifier: 0000-0003-2700-7459 0000-0002-4429-6507
Record's date: 2023-09-02
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://www.nmcd-journal.com/article/S0939-4753(19)30092-4/abstract
Papper original source: Nutrition Metabolism And Cardiovascular Diseases. 29 (7): 676-683
APA: Bazal P; Gea A; Martínez-González MA; Salas-Salvadó J; Asensio EM; Muñoz-Bravo C; Fiol M; Muñoz MA; Lapetra J; Serra-Majem LL; Pintó X; González JI; B (2019). Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study. Nutrition Metabolism And Cardiovascular Diseases, 29(7), 676-683. DOI: 10.1016/j.numecd.2019.03.007
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.1016/j.numecd.2019.03.007
Entity: Universitat Rovira i Virgili
Journal publication year: 2019
Publication Type: Journal Publications