Articles producció científica> Bioquímica i Biotecnologia

Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study

  • Identification data

    Identifier: imarina:5098062
    Authors:
    Bazal PGea AMartínez-González MASalas-Salvadó JAsensio EMMuñoz-Bravo CFiol MMuñoz MALapetra JSerra-Majem LLPintó XGonzález JIBecerra-Tomás NFitó MRos EAlonso-Gómez ARuiz-Canela M
    Abstract:
    © 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University Background and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP)(10–30 g/d in men and 5–15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR)with 95% confidence intervals (95% CI)of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67–1.37), adherents to MADP (HR: 1.15 95%CI: 0.75–1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53–1.58), compared with non-drinkers. Conclusions: In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption)was not associated with an increased incidence of AF. Clinical trials: URL: http://www.controlled-trials.com. Unique identifier: ISRCTN35739639.
  • Others:

    Author, as appears in the article.: Bazal P; Gea A; Martínez-González MA; Salas-Salvadó J; Asensio EM; Muñoz-Bravo C; Fiol M; Muñoz MA; Lapetra J; Serra-Majem LL; Pintó X; González JI; Becerra-Tomás N; Fitó M; Ros E; Alonso-Gómez A; Ruiz-Canela M
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Becerra Tomás, Nerea / Salas Salvadó, Jorge
    Keywords: Adult Adverse event Aged Aged, 80 and over Alcohol Alcohol consumption Alcohol drinking Antioxidant Article Atrial fibrillation Body mass Cardiovascular risk Clinical trial Depression Diet, mediterranean Drinking behavior Electrocardiogram Feeding behavior Female Follow up Food frequency questionnaire Hazard ratio Heart disease Human Humans Hypertension Incidence Major clinical study Male Mediterranean Mediterranean diet Middle aged Multicenter study Physical activity Priority journal Prognosis Prospective studies Prospective study Red wine Risk assessment Risk factor Risk factors Self report Spain Time factor Time factors Very elderly Wine
    Abstract: © 2019 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University Background and aims: There is ongoing controversy about the effect of a low to moderate alcohol consumption on atrial fibrillation (AF). Our aim is to assess the association between adherence to a Mediterranean alcohol drinking pattern and AF incidence. Methods and results: A total 6527 out of the 7447 participants in the PREDIMED trial met our inclusion criteria. A validated frequency food questionnaire was used to measure alcohol consumption. Participants were classified as non-drinkers, Mediterranean alcohol drinking pattern (MADP)(10–30 g/d in men and 5–15 g/day in women, preferably red wine consumption with low spirits consumption), low-moderate drinking (<30 g/day men y and < 15 g/day women), and heavy drinking. We performed multivariable Cox regression models to estimate hazard ratios (HR)with 95% confidence intervals (95% CI)of incident AF according to alcohol drinking patterns. After a mean follow up of 4.4 years, 241 new incident AF cases were confirmed. Alcohol consumption was not associated to AF incidence among low-moderate drinkers (HR: 0.96; 95%CI: 0.67–1.37), adherents to MADP (HR: 1.15 95%CI: 0.75–1.75), or heavy drinkers (HR: 0.92; 95%CI: 0.53–1.58), compared with non-drinkers. Conclusions: In a high cardiovascular risk adult population, a Mediterranean alcohol consumption pattern (low to moderate red wine consumption)was not associated with an increased incidence of AF. Clinical trials: URL: http://www.controlled-trials.com. Unique identifier: ISRCTN35739639.
    Thematic Areas: Cardiac & cardiovascular systems Cardiology and cardiovascular medicine Ciências ambientais Ciências biológicas i Ciências biológicas ii Educação física Endocrinology & metabolism Endocrinology, diabetes and metabolism Enfermagem Farmacia General medicine Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Medicine (miscellaneous) Nutrição Nutrition & dietetics Nutrition and dietetics Saúde coletiva Serviço social
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: jordi.salas@urv.cat nerea.becerra@urv.cat
    ISSN: 15903729
    Author identifier: 0000-0003-2700-7459 0000-0002-4429-6507
    Record's date: 2023-09-02
    Papper version: info:eu-repo/semantics/acceptedVersion
    Link to the original source: https://www.nmcd-journal.com/article/S0939-4753(19)30092-4/abstract
    Papper original source: Nutrition Metabolism And Cardiovascular Diseases. 29 (7): 676-683
    APA: Bazal P; Gea A; Martínez-González MA; Salas-Salvadó J; Asensio EM; Muñoz-Bravo C; Fiol M; Muñoz MA; Lapetra J; Serra-Majem LL; Pintó X; González JI; B (2019). Mediterranean alcohol-drinking pattern, low to moderate alcohol intake and risk of atrial fibrillation in the PREDIMED study. Nutrition Metabolism And Cardiovascular Diseases, 29(7), 676-683. DOI: 10.1016/j.numecd.2019.03.007
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1016/j.numecd.2019.03.007
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2019
    Publication Type: Journal Publications
  • Keywords:

    Cardiac & Cardiovascular Systems,Cardiology and Cardiovascular Medicine,Endocrinology & Metabolism,Endocrinology, Diabetes and Metabolism,Medicine (Miscellaneous),Nutrition & Dietetics,Nutrition and Dietetics
    Adult
    Adverse event
    Aged
    Aged, 80 and over
    Alcohol
    Alcohol consumption
    Alcohol drinking
    Antioxidant
    Article
    Atrial fibrillation
    Body mass
    Cardiovascular risk
    Clinical trial
    Depression
    Diet, mediterranean
    Drinking behavior
    Electrocardiogram
    Feeding behavior
    Female
    Follow up
    Food frequency questionnaire
    Hazard ratio
    Heart disease
    Human
    Humans
    Hypertension
    Incidence
    Major clinical study
    Male
    Mediterranean
    Mediterranean diet
    Middle aged
    Multicenter study
    Physical activity
    Priority journal
    Prognosis
    Prospective studies
    Prospective study
    Red wine
    Risk assessment
    Risk factor
    Risk factors
    Self report
    Spain
    Time factor
    Time factors
    Very elderly
    Wine
    Cardiac & cardiovascular systems
    Cardiology and cardiovascular medicine
    Ciências ambientais
    Ciências biológicas i
    Ciências biológicas ii
    Educação física
    Endocrinology & metabolism
    Endocrinology, diabetes and metabolism
    Enfermagem
    Farmacia
    General medicine
    Interdisciplinar
    Medicina i
    Medicina ii
    Medicina iii
    Medicina veterinaria
    Medicine (miscellaneous)
    Nutrição
    Nutrition & dietetics
    Nutrition and dietetics
    Saúde coletiva
    Serviço social
    15903729
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