Articles producció científica> Ciències Mèdiques Bàsiques

Occurrence of ochroconis and verruconis species in clinical specimens from the United States

  • Identification data

    Identifier: imarina:5128335
    Authors:
    Giraldo, AlejandraSutton, Deanna ASamerpitak, Kittipande Hoog, G SybrenWiederhold, Nathan PGuarro, JosepGene, Josepa
    Abstract:
    Ochroconis is a dematiaceous fungus able to infect immunocompetent people. Recently, the taxonomy of the genus has been reevaluated, and the most relevant species, Ochroconis gallopava, was transferred to the new genus Verruconis. Due to the important clinical implications of these fungi and based on the recent classification, it was of interest to know the spectra of Ochroconis and Verruconis species in clinical samples received in a reference laboratory in the United States. A set of 51 isolates was identified morphologically and molecularly based on sequence analyses of the nuclear ribosomal RNA (nrRNA), actin, and β-tubulin genes. Verruconis gallopava was the most common species (68.6%), followed by Ochroconis mirabilis (21.5%). One isolate of Ochroconis cordanae was found, being reported for the first time in a clinical setting. The most common anatomical site of isolation was the lower respiratory tract (58.8%), followed by superficial and deep tissues at similar frequencies (21.6 and 19.6%, respectively). Interestingly, three new species were found, which are Ochroconis olivacea and Ochroconis ramosa from clinical specimens and Ochroconis icarus of an environmental origin. The in vitro antifungal susceptibilities of eight antifungal drugs against the Ochroconis isolates revealed that terbinafine and micafungin were the most active drugs.
  • Others:

    Author, as appears in the article.: Giraldo, Alejandra; Sutton, Deanna A; Samerpitak, Kittipan; de Hoog, G Sybren; Wiederhold, Nathan P; Guarro, Josep; Gene, Josepa
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Gené Díaz, Josepa / Guarro Artigas, Josep
    Abstract: Ochroconis is a dematiaceous fungus able to infect immunocompetent people. Recently, the taxonomy of the genus has been reevaluated, and the most relevant species, Ochroconis gallopava, was transferred to the new genus Verruconis. Due to the important clinical implications of these fungi and based on the recent classification, it was of interest to know the spectra of Ochroconis and Verruconis species in clinical samples received in a reference laboratory in the United States. A set of 51 isolates was identified morphologically and molecularly based on sequence analyses of the nuclear ribosomal RNA (nrRNA), actin, and β-tubulin genes. Verruconis gallopava was the most common species (68.6%), followed by Ochroconis mirabilis (21.5%). One isolate of Ochroconis cordanae was found, being reported for the first time in a clinical setting. The most common anatomical site of isolation was the lower respiratory tract (58.8%), followed by superficial and deep tissues at similar frequencies (21.6 and 19.6%, respectively). Interestingly, three new species were found, which are Ochroconis olivacea and Ochroconis ramosa from clinical specimens and Ochroconis icarus of an environmental origin. The in vitro antifungal susceptibilities of eight antifungal drugs against the Ochroconis isolates revealed that terbinafine and micafungin were the most active drugs.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Odontología Microbiology (medical) Microbiology Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Interdisciplinar Farmacia Ensino Engenharias ii Enfermagem Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciência de alimentos Ciência da computação Biotecnología Biodiversidade
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: josepa.gene@urv.cat
    Author identifier: 0000-0001-6195-9299
    Record's date: 2024-09-07
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://journals.asm.org/doi/10.1128/jcm.02027-14
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Journal Of Clinical Microbiology. 52 (12): 4189-4201
    APA: Giraldo, Alejandra; Sutton, Deanna A; Samerpitak, Kittipan; de Hoog, G Sybren; Wiederhold, Nathan P; Guarro, Josep; Gene, Josepa (2014). Occurrence of ochroconis and verruconis species in clinical specimens from the United States. Journal Of Clinical Microbiology, 52(12), 4189-4201. DOI: 10.1128/JCM.02027-14
    Article's DOI: 10.1128/JCM.02027-14
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2014
    Publication Type: Journal Publications
  • Keywords:

    Microbiology,Microbiology (Medical)
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Odontología
    Microbiology (medical)
    Microbiology
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Interdisciplinar
    Farmacia
    Ensino
    Engenharias ii
    Enfermagem
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciência de alimentos
    Ciência da computação
    Biotecnología
    Biodiversidade
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