Articles producció científicaBioquímica i Biotecnologia

Proanthocyanidins in health and disease

  • Identification data

    Identifier:  imarina:5129464
    Handle: https://hdl.handle.net/20.500.11797/imarina5129464
    Authors:  Bladé, C; Aragonès, G; Arola-Arnal, A; Muguerza, B; Bravo, FI; Salvadó, MJ; Arola, L; Suárez, M
    Abstract:
    © 2016 International Union of Biochemistry and Molecular Biology. Proanthocyanidins (PAs) are the most abundant flavonoids in the human diet. Several epidemiological studies connect PA consumption and health benefits and the designation of PAs as healthy compounds started at the early stages of the 20th century. The beneficial health properties of PAs are attributed to their conjugated and colonic metabolites. Therefore, gut microbial compositions can determine the effectiveness of PAs. Reciprocally, dietary polyphenols can act as prebiotics. Recently, it has also been described that PAs modulate the circadian rhythm. Biochemical and epigenetic mechanisms, including the modulation of microRNAs, allow PAs to modulate cell functionality. PA effects in metabolic diseases are also reviewed.

  • Others:

    Link to the original source: https://iubmb.onlinelibrary.wiley.com/doi/10.1002/biof.1249
    APA: Bladé, C; Aragonès, G; Arola-Arnal, A; Muguerza, B; Bravo, FI; Salvadó, MJ; Arola, L; Suárez, M (2016). Proanthocyanidins in health and disease. Biofactors, 42(1), 5-12. DOI: 10.1002/biof.1249
    Paper original source: Biofactors. 42 (1): 5-12
    Article's DOI: 10.1002/biof.1249
    Journal publication year: 2016-02-01
    Entity: Universitat Rovira i Virgili
    Paper version: info:eu-repo/semantics/submittedVersion
    Record's date: 2026-05-09
    URV's Author/s: Aragonès Bargalló, Gerard / Arola Arnal, Anna / Arola Ferrer, Luis Maria / BLADÉ SEGARRA, MARIA CINTA / Bravo Vázquez, Francisca Isabel / Muguerza Marquínez, Maria Begoña / Salvadó Rovira, Maria Josepa / Suárez Recio, Manuel
    Department: Bioquímica i Biotecnologia
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Publication Type: Journal Publications
    Author, as appears in the article.: Bladé, C; Aragonès, G; Arola-Arnal, A; Muguerza, B; Bravo, FI; Salvadó, MJ; Arola, L; Suárez, M
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Thematic Areas: Molecular medicine, Medicine (miscellaneous), Medicina i, Endocrinology & metabolism, Clinical biochemistry, Ciências biológicas i, Biotecnología, Biochemistry & molecular biology, Biochemistry
    Author's mail: lluis.arola@urv.cat, lluis.arola@urv.cat, manuel.suarez@urv.cat, manuel.suarez@urv.cat, franciscaisabel.bravo@urv.cat, franciscaisabel.bravo@urv.cat, anna.arola@urv.cat, anna.arola@urv.cat, gerard.aragones@urv.cat, gerard.aragones@urv.cat, begona.muguerza@urv.cat, begona.muguerza@urv.cat

  • Keywords:

    Proanthocyanidins
    Prebiotics
    Polyphenols
    Molecular mechanisms
    Microbiota
    Metabolic diseases
    Humans
    Flavonoids
    Diet
    Colon
    Circadian rhythms
    Circadian rhythm
    Biochemistry
    Biochemistry & Molecular Biology
    Clinical Biochemistry
    Endocrinology & Metabolism
    Medicine (Miscellaneous)
    Molecular Medicine
    Medicina i
    Ciências biológicas i
    Biotecnología

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