Articles producció científica> Ciències Mèdiques Bàsiques

Marine Lipids on Cardiovascular Diseases and Other Chronic Diseases Induced by Diet: An Insight Provided by Proteomics and Lipidomics

  • Identification data

    Identifier: imarina:5131824
    Authors:
    Méndez L., Dasilva G., Taltavull N., Romeu M., Medina I.
    Abstract:
    Marine lipids, especially ω-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have largely been linked to prevention of diet-induced diseases. The anti-inflammatory and hypolipidemic properties of EPA and DHA supplementation have been well-described. However, there is still a significant lack of information about their particular mechanism of action. Furthermore, repeated meta-analyses have not shown conclusive results in support of their beneficial health effects. Modern "omics" approaches, namely proteomics and lipidomics, have made it possible to identify some of the mechanisms behind the benefits of marine lipids in the metabolic syndrome and related diseases, i.e., cardiovascular diseases and type 2 diabetes. Although until now their use has been scarce, these "omics" have brought new insights in this area of nutrition research. The purpose of the present review is to comprehensively show the research articles currently available in the literature which have specifically applied proteomics, lipidomics or both approaches to investigate the role of marine lipids intake in the prevention or palliation of these chronic pathologies related to diet. The methodology adopted, the class of marine lipids examined, the diet-related disease studied, and the main findings obtained in each investigation will be reviewed.
  • Others:

    Author, as appears in the article.: Méndez L., Dasilva G., Taltavull N., Romeu M., Medina I.
    Department: Ciències Mèdiques Bàsiques
    URV's Author/s: Romeu Ferran, Marta / Taltavull Anglada, Núria
    Keywords: Type 2 diabetes Proteomics Metabolic syndrome Marine lipids Lipidomics Epa Dha Cardiovascular disease proteomics metabolic syndrome marine lipids lipidomics epa dha cardiovascular disease
    Abstract: Marine lipids, especially ω-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have largely been linked to prevention of diet-induced diseases. The anti-inflammatory and hypolipidemic properties of EPA and DHA supplementation have been well-described. However, there is still a significant lack of information about their particular mechanism of action. Furthermore, repeated meta-analyses have not shown conclusive results in support of their beneficial health effects. Modern "omics" approaches, namely proteomics and lipidomics, have made it possible to identify some of the mechanisms behind the benefits of marine lipids in the metabolic syndrome and related diseases, i.e., cardiovascular diseases and type 2 diabetes. Although until now their use has been scarce, these "omics" have brought new insights in this area of nutrition research. The purpose of the present review is to comprehensively show the research articles currently available in the literature which have specifically applied proteomics, lipidomics or both approaches to investigate the role of marine lipids intake in the prevention or palliation of these chronic pathologies related to diet. The methodology adopted, the class of marine lipids examined, the diet-related disease studied, and the main findings obtained in each investigation will be reviewed.
    Thematic Areas: Zootecnia / recursos pesqueiros Química Pharmacology, toxicology and pharmaceutics (miscellaneous) Pharmacology & pharmacy Pharmaceutical science Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Geociências Farmacia Engenharias iii Engenharias ii Educação física Drug discovery Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, medicinal Biotecnología Biodiversidade Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 16603397
    Author's mail: nuria.taltavull@urv.cat marta.romeu@urv.cat
    Author identifier: 0000-0002-3340-2650 0000-0002-2131-1858
    Record's date: 2024-09-07
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.mdpi.com/1660-3397/15/8/258
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Papper original source: Marine Drugs. 15 (8):
    APA: Méndez L., Dasilva G., Taltavull N., Romeu M., Medina I. (2017). Marine Lipids on Cardiovascular Diseases and Other Chronic Diseases Induced by Diet: An Insight Provided by Proteomics and Lipidomics. Marine Drugs, 15(8), -. DOI: 10.3390/md15080258
    Article's DOI: 10.3390/md15080258
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2017
    Publication Type: Journal Publications
  • Keywords:

    Chemistry, Medicinal,Drug Discovery,Pharmaceutical Science,Pharmacology & Pharmacy,Pharmacology, Toxicology and Pharmaceutics (Miscellaneous)
    Type 2 diabetes
    Proteomics
    Metabolic syndrome
    Marine lipids
    Lipidomics
    Epa
    Dha
    Cardiovascular disease
    proteomics
    metabolic syndrome
    marine lipids
    lipidomics
    epa
    dha
    cardiovascular disease
    Zootecnia / recursos pesqueiros
    Química
    Pharmacology, toxicology and pharmaceutics (miscellaneous)
    Pharmacology & pharmacy
    Pharmaceutical science
    Nutrição
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Interdisciplinar
    Geociências
    Farmacia
    Engenharias iii
    Engenharias ii
    Educação física
    Drug discovery
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Chemistry, medicinal
    Biotecnología
    Biodiversidade
    Astronomia / física
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