Author, as appears in the article.: Méndez L., Dasilva G., Taltavull N., Romeu M., Medina I.
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Romeu Ferran, Marta / Taltavull Anglada, Núria
Keywords: Type 2 diabetes Proteomics Metabolic syndrome Marine lipids Lipidomics Epa Dha Cardiovascular disease proteomics metabolic syndrome marine lipids lipidomics epa dha cardiovascular disease
Abstract: Marine lipids, especially ω-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have largely been linked to prevention of diet-induced diseases. The anti-inflammatory and hypolipidemic properties of EPA and DHA supplementation have been well-described. However, there is still a significant lack of information about their particular mechanism of action. Furthermore, repeated meta-analyses have not shown conclusive results in support of their beneficial health effects. Modern "omics" approaches, namely proteomics and lipidomics, have made it possible to identify some of the mechanisms behind the benefits of marine lipids in the metabolic syndrome and related diseases, i.e., cardiovascular diseases and type 2 diabetes. Although until now their use has been scarce, these "omics" have brought new insights in this area of nutrition research. The purpose of the present review is to comprehensively show the research articles currently available in the literature which have specifically applied proteomics, lipidomics or both approaches to investigate the role of marine lipids intake in the prevention or palliation of these chronic pathologies related to diet. The methodology adopted, the class of marine lipids examined, the diet-related disease studied, and the main findings obtained in each investigation will be reviewed.
Thematic Areas: Zootecnia / recursos pesqueiros Química Pharmacology, toxicology and pharmaceutics (miscellaneous) Pharmacology & pharmacy Pharmaceutical science Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Geociências Farmacia Engenharias iii Engenharias ii Educação física Drug discovery Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Chemistry, medicinal Biotecnología Biodiversidade Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 16603397
Author's mail: nuria.taltavull@urv.cat marta.romeu@urv.cat
Author identifier: 0000-0002-3340-2650 0000-0002-2131-1858
Record's date: 2024-09-07
Papper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Marine Drugs. 15 (8):
APA: Méndez L., Dasilva G., Taltavull N., Romeu M., Medina I. (2017). Marine Lipids on Cardiovascular Diseases and Other Chronic Diseases Induced by Diet: An Insight Provided by Proteomics and Lipidomics. Marine Drugs, 15(8), -. DOI: 10.3390/md15080258
Entity: Universitat Rovira i Virgili
Journal publication year: 2017
Publication Type: Journal Publications