Author, as appears in the article.: Lligadas G, Enayati M, Grama S, Smail R, Sherman SE, Percec V
Department: Química Analítica i Química Orgànica
e-ISSN: 1526-4602
URV's Author/s: Lligadas Puig, Gerard
Keywords: Vinyl-chloride Single-electron-transfer Methyl acrylate Living radical polymerization Free radical reactions Dramatic acceleration Divergent synthesis Dendritic macromolecules Cu(0) wire Conventional monomers Biology Amide functional initiators
Abstract: To continue expanding the use of Single Electron Transfer-Living Radical Polymerization (SET-LRP) in applications at the interface between macromolecular science, biomacromolecules, biology and medicine, it is essential to develop novel initiators that do not compromise the structural stability of synthesized polymers in biological environments. Here, we report that stable 2-bromopropionyl peptoid-type initiators such as 1,4-bis(2-bromopropionyl)piperazine and 4-(2-bromopropionyl)morpholine are an alternative that meets the standards reached by the well-known secondary and tertiary ¿-haloester-type initiators in terms of excellent control over molecular weight evolution and distribution as well as polymer chain ends. SET-LRP methodologies in organic, aqueous, and biphasic organic-aqueous media were evaluated for this purpose.
Thematic Areas: Química Polymers and plastics Polymer science Medicina ii Materials chemistry Materiais Interdisciplinar Farmacia Engenharias iv Engenharias ii Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Chemistry, organic Biotecnología Biomaterials Bioengineering Biochemistry & molecular biology Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 1525-7797
Author's mail: gerard.lligadas@urv.cat
Author identifier: 0000-0002-8519-1840
Record's date: 2024-09-07
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://pubs.acs.org/doi/10.1021/acs.biomac.7b00722
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Biomacromolecules. 18 (8): 2610-2622
APA: Lligadas G, Enayati M, Grama S, Smail R, Sherman SE, Percec V (2017). Ultrafast SET-LRP with Peptoid Cytostatic Drugs as Monofunctional and Bifunctional Initiators. Biomacromolecules, 18(8), 2610-2622. DOI: 10.1021/acs.biomac.7b00722
Article's DOI: 10.1021/acs.biomac.7b00722
Entity: Universitat Rovira i Virgili
Journal publication year: 2017
Publication Type: Journal Publications
Repositori URV