**Author, as appears in the article.: **López J., Fortuny G., Puigjaner D., Herrero J., Marimon F.

**Department: **Medicina i Cirurgia Enginyeria Informàtica i Matemàtiques Enginyeria Química

**URV's Author/s: **Fortuny Anguera, Gerard / Herrero Sabartés, Juan / López Besora, Josep Maria / Puigjaner Riba, Maria Dolores

**Keywords: ** Wall shear stress Non-newtonian viscosity model Inferior vena cava filters Hemodynamics Drag coefficients Computational fluid dynamics non-newtonian viscosity model inferior vena cava filters hemodynamics drag coefficients computational fluid dynamics

**Abstract: **Computational fluid dynamics was used to simulate the flow of blood within an inferior vena cava (IVC) geometry model that was reconstructed from computed tomography images obtained from a real patient. The main novelty of the present work is that we simulated the implantation of four different filter models in this real- istic IVC geometry. We considered different blood flow rates in the range between Vin= 20 and Vin= 80cm3∕s and all simulations were performed with both the Newtonian and a non-Newtonian model for the blood viscosity. We compared the hemodynamics performance of the different filter models and we paid a special atten- tion to the total drag force, Fd, exerted by the blood flow on the filter surface. This force is the sum of two contributions: the viscous skin friction force, which was found to be roughly proportional to the filter surface area, and the pressure force, which depended on the particular filter geometry design. The Fd force is relevant because it must be balanced by the total force exerted by the filter hooks/struts on the IVC wall at the attachment locations. For the highest Vin value investigated, the variation in Fd among filters was from 116 to 308 dyne. We also showed how the present results can be extrapolated to obtain good estimates of the drag forces if the blood viscosity levels change, i.e., if the patient with a filter implanted is treated with anticoagulant therapy.

**Thematic Areas: ** Software Molecular biology Modeling and simulation Medicina ii Medicina i Mathematics, interdisciplinary applications Mathematical & computational biology Interdisciplinar Engineering, biomedical Engenharias iii Engenharias i Educação física Computational theory and mathematics Ciências biológicas ii Ciência da computação Biomedical engineering Applied mathematics

**ISSN: **20407939

**Author's mail: **josep.m.lopez@urv.cat joan.herrero@urv.cat dolors.puigjaner@urv.cat gerard.fortuny@urv.cat

**Author identifier: **0000-0001-7541-8936 0000-0001-8501-1187 0000-0001-5251-2022 0000-0002-2500-7386

**Record's date: **2023-02-18

**Journal volume: **34

**Papper version: **info:eu-repo/semantics/acceptedVersion

**Link to the original source: **https://onlinelibrary.wiley.com/doi/abs/10.1002/cnm.2990

**Licence document URL: **http://repositori.urv.cat/ca/proteccio-de-dades/

**Papper original source: **International Journal For Numerical Methods In Biomedical Engineering. 34 (7): e2990-

**APA: **López J., Fortuny G., Puigjaner D., Herrero J., Marimon F. (2018). A comparative CFD study of four inferior vena cava filters. International Journal For Numerical Methods In Biomedical Engineering, 34(7), e2990-. DOI: 10.1002/cnm.2990

**Article's DOI: **10.1002/cnm.2990

**Entity: **Universitat Rovira i Virgili

**Journal publication year: **2018

**First page: **Article number e2990

**Publication Type: **Journal Publications