Author, as appears in the article.: Gils Contreras A, Bonada Sanjaume A, Montero Jaime M, Rabassa Soler A, Sabench Pereferrer F, Molina López A, Becerra Tomás N, Del Castillo Déjardin D, Salas-Salvadó J
Department: Medicina i Cirurgia Bioquímica i Biotecnologia
URV's Author/s: Becerra Tomás, Nerea / Bonada Sanjaume, Anna Maria / Del Castillo Déjardin, Daniel / Gils Contreras, Anna / MOLINA LÓPEZ, ALICIA / Montero Jaime, Manuel Jesus / Rabassa Soler, Antonio / Sabench Pereferrer, Fàtima / Salas Salvadó, Jorge
Keywords: Weight loss Preoperative diet Morbid obesity Liver size Bariatric surgery preoperative diet liver size bariatric surgery
Abstract: OBJECTIVE: To assess which type of preoperative dietary strategy is most effective in reducing liver volume and assessing its influence on different biochemical parameters and on surgical complications in individuals undergoing bariatric surgery. METHODS: Parallel randomized trial comparing the effect of a very low calorie diet (VLCD) and a low calorie diet (LCD) for a period of 21 days before surgery on hepatic volume, anthropometric and biochemical parameters. Compliance and tolerance to the diets, surgical complications, and hospital stay were also determined. RESULTS: Eighty-six morbid obese participants undergoing bariatric surgery were randomized. The hepatic volume was significantly reduced in both intervention groups, but no differences in changes between groups were detected. The reduction in the hepatic volume was higher in those patients with a baseline hepatic volume > 3 L compared to those with < 3 L (adjusted P value < 0.001). The percentages of total weight lost were 5.8 and 4.2% (adjusted P value = 0.004) for participants on the VLCD and LCD, respectively. There were no differences between groups for any of the biochemical parameters analyzed, nor in the number of surgical complications nor the length of hospital stay. Adherence to the diet was good; nevertheless, participants in the VLCD intervention showed worse tolerance. CONCLUSIONS: In subjects with morbid obesity undergoing bariatric surgery, compared to a LCD, a preoperative 21-day intervention with VLCD is more effective in terms of reducing total body weight but not in terms of reducing the liver volume. Both types of preoperative diets have similar effects on clinical biochemical parameters, rate of surgical complications, and hospital length stay.
Thematic Areas: Surgery Saúde coletiva Psicología Odontología Nutrition and dietetics Nutrição Medicina iii Medicina ii Medicina i Interdisciplinar General medicine Farmacia Engenharias iv Enfermagem Endocrinology, diabetes and metabolism Educação física Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 09608923
Author's mail: antonio.rabassa@urv.cat manueljesus.montero@urv.cat annamaria.bonada@urv.cat danieldel.castillo@urv.cat nerea.becerra@urv.cat fatima.sabench@urv.cat jordi.salas@urv.cat
Author identifier: 0000-0003-0456-3102 0000-0001-7024-7824 0000-0002-4429-6507 0000-0002-9262-8756 0000-0003-2700-7459
Record's date: 2024-09-07
Papper version: info:eu-repo/semantics/acceptedVersion
Link to the original source: https://link.springer.com/article/10.1007/s11695-018-3413-7
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Obesity Surgery. 28 (12): 3756-3768
APA: Gils Contreras A, Bonada Sanjaume A, Montero Jaime M, Rabassa Soler A, Sabench Pereferrer F, Molina López A, Becerra Tomás N, Del Castillo Déjardin D, (2018). Effects of Two Preoperatory Weight Loss Diets on Hepatic Volume, Metabolic Parameters, and Surgical Complications in Morbid Obese Bariatric Surgery Candidates: a Randomized Clinical Trial. Obesity Surgery, 28(12), 3756-3768. DOI: 10.1007/s11695-018-3413-7
Article's DOI: 10.1007/s11695-018-3413-7
Entity: Universitat Rovira i Virgili
Journal publication year: 2018
Publication Type: Journal Publications