Author, as appears in the article.: Gibert-Ramos A, Crescenti A, Salvadó MJ.
Department: Bioquímica i Biotecnologia
e-ISSN: 2072-6643
URV's Author/s: Salvadó Rovira, Maria Josepa
Keywords: Xenohormesis Seasonality Obesity Fruit consumption Adipose tissue seasonality photoperiod obesity fruit consumption cherry cafeteria diet adipose tissue
Abstract: The aim of this study was to determine whether the consumption of cherry out of its normal harvest photoperiod affects adipose tissue, increasing the risk of obesity. Fischer 344 rats were held over a long day (LD) or a short day (SD), fed a standard diet (STD), and treated with a cherry lyophilizate (CH) or vehicle (VH) (n = 6). Biometric measurements, serum parameters, gene expression in white (RWAT) and brown (BAT) adipose tissues, and RWAT histology were analysed. A second experiment with similar conditions was performed (n = 10) but with a cafeteria diet (CAF). In the STD experiment, Bmal1 and Cry1 were downregulated in the CHSD group compared to the VHSD group. Pparα expression was downregulated while Ucp1 levels were higher in the BAT of the CHSD group compared to the VHSD group. In the CAF-fed rats, glucose and insulin serum levels increased, and the expression levels of lipogenesis and lipolysis genes in RWAT were downregulated, while the adipocyte area increased and the number of adipocytes diminished in the CHSD group compared to the VHSD group. In conclusion, we show that the consumption of cherry out of season influences the metabolism of adipose tissue and promotes fat accumulation when accompanied by an obesogenic diet.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20726643
Author's mail: mariajosepa.salvado@urv.cat
Author identifier: 0000-0003-3883-3326
Record's date: 2024-07-20
Journal volume: 10
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/10/8/1102
Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Nutrients. 10 (8):
APA: Gibert-Ramos A, Crescenti A, Salvadó MJ. (2018). Consumption of Cherry out of Season Changes White Adipose Tissue Gene Expression and Morphology to a Phenotype Prone to Fat Accumulation. Nutrients, 10(8), -. DOI: 10.3390/nu10081102
Article's DOI: 10.3390/nu10081102
Entity: Universitat Rovira i Virgili
Journal publication year: 2018
Publication Type: Journal Publications
Repositori URV