Author, as appears in the article.: Livesey G; Taylor R; Livesey HF; Buyken AE; Jenkins DJA; Augustin LSA; Sievenpiper JL; Barclay AW; Liu S; Wolever TMS; Willett WC; Brighenti F; Salvadó JS; Björck I; Rizkalla SW; Riccardi G; La Vecchia C; Ceriello A; Trichopoulou A; Poli A; Astrup A; Kendall CWC; Ha MA; Sinnott SB; Miller JCB
Department: Bioquímica i Biotecnologia
URV's Author/s: Salas Salvadó, Jorge
Keywords: alcohol cohort studies dietary fiber epidemiology glycemic index glycemic load meta-analysis protein Alcohol Alcohol intake Carbohydrate intake Chronic disease Cohort studies Dietary fiber Epidemiology Fiber intake Food-frequency questionnaire Glycemic index Glycemic load Joint association Life-style Mellitus Meta-analysis Meta?analysis Population Protein Trend estimation Type 2 diabetes
Abstract: Published meta-analyses indicate significant but inconsistent incident type-2 diabetes(T2D)-dietary glycemic index (GI) and glycemic load (GL) risk ratios or risk relations (RR). It is nowover a decade ago that a published meta-analysis used a predefined standard to identify validstudies. Considering valid studies only, and using random effects dose-response meta-analysis(DRM) while withdrawing spurious results (p < 0.05), we ascertained whether these relationswould support nutrition guidance, specifically for an RR > 1.20 with a lower 95% confidence limit>1.10 across typical intakes (approximately 10th to 90th percentiles of population intakes). Thecombined T2D-GI RR was 1.27 (1.15-1.40) (p < 0.001, n = 10 studies) per 10 units GI, while that forthe T2D-GL RR was 1.26 (1.15-1.37) (p < 0.001, n = 15) per 80 g/d GL in a 2000 kcal (8400 kJ) diet.The corresponding global DRM using restricted cubic splines were 1.87 (1.56-2.25) (p < 0.001, n =10) and 1.89 (1.66-2.16) (p < 0.001, n = 15) from 47.6 to 76.1 units GI and 73 to 257 g/d GL in a 2000kcal diet, respectively. In conclusion, among adults initially in good health, diets higher in GI or GLwere robustly associated with incident T2D. Together with mechanistic and other data, thissupports that consideration should be given to these dietary risk factors in nutrition advice.Concerning the public health relevance at the global level, our evidence indicates that GI and GLare substantial food markers predicting the development of T2D worldwide, for persons ofEuropean ancestry and of East Asian ancestry.
Thematic Areas: Biotecnología Ciência de alimentos Ciências agrárias i Ciências biológicas i Ciências biológicas ii Ciências biológicas iii Economia Educação física Enfermagem Engenharias ii Engenharias iv Farmacia Food science Interdisciplinar Medicina i Medicina ii Medicina iii Medicina veterinaria Nutrição Nutrition & dietetics Nutrition and dietetics Planejamento urbano e regional / demografia Psicología Química Saúde coletiva Zootecnia / recursos pesqueiros
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jordi.salas@urv.cat
ISSN: 20726643
Author identifier: 0000-0003-2700-7459
Record's date: 2023-02-18
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/11/6/1280
Papper original source: Nutrients. 11 (6):
APA: Livesey G; Taylor R; Livesey HF; Buyken AE; Jenkins DJA; Augustin LSA; Sievenpiper JL; Barclay AW; Liu S; Wolever TMS; Willett WC; Brighenti F; Salvad (2019). Dietary Glycemic Index and Load and the Risk of Type 2 Diabetes: A Systematic Review and Updated Meta-Analyses of Prospective Cohort Studies. Nutrients, 11(6), -. DOI: 10.3390/nu11061280
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.3390/nu11061280
Entity: Universitat Rovira i Virgili
Journal publication year: 2019
Publication Type: Journal Publications
Repositori URV