Author, as appears in the article.: Cunillera A; Ruiz A; Godard C
Department: Química Física i Inorgànica
URV's Author/s: Godard, Cyril / Ruiz Manrique, Maria Aurora
Project code: CTQ2016-75016-R
Keywords: Β-amino acids Tandem Recent progress Intermolecular amination Hydrogenation Hydroformylation Hydroaminomethylation Derivatives Bonds Beta-amino acids Asymmetric hydrogenation ?-amino acids
Abstract: © 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim The synthesis of β2,2-amino esters was successfully achieved via Rh-catalysed regioselective hydroaminomethylation of methyl methacrylate with secondary amines using the neutral precursor [Rh(acac)(CO)2]. In this process, the presence of molecular sieves revealed crucial in order to access the final amino ester. For the synthesis of products containing aniline derivatives, the use of the cationic precursor [Rh(COD)2]BF4 and MeCgPPh phosphine as ligand was necessary in a mixture of toluene/DCE as solvent. Effects of the steric and electronic properties of the amines were observed during this study. Interestingly, poisoning effect of CO in the hydrogenation of the imine intermediate was observed when benzyl amine was used. (Figure presented.).
Thematic Areas: Química Organic chemistry Materiais Engenharias iv Engenharias ii Ciências biológicas ii Ciência de alimentos Chemistry, organic Chemistry, applied Catalysis Biodiversidade Astronomia / física
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 16154150
Author's mail: mariaaurora.ruiz@urv.cat cyril.godard@urv.cat
Author identifier: 0000-0002-1563-292X 0000-0001-5762-4904
Record's date: 2023-02-18
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://onlinelibrary.wiley.com/doi/full/10.1002/adsc.201900642
Funding program: PROGRAMA ESTATAL DE INVESTIGACIÓN, DESARROLLO E INNOVACIÓN ORIENTADA A LOS RETOS DE LA SOCIEDAD
Papper original source: Advanced Synthesis & Catalysis. 361 (18): 4201-4207
APA: Cunillera A; Ruiz A; Godard C (2019). Synthesis of β2,2-Amino esters via Rh-Catalysed Regioselective Hydroaminomethylation. Advanced Synthesis & Catalysis, 361(18), 4201-4207. DOI: 10.1002/adsc.201900642
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Acronym: ECO2VALCAT
Article's DOI: 10.1002/adsc.201900642
Entity: Universitat Rovira i Virgili
Journal publication year: 2019
Funding program action: VALORIZACION EFICIENTE DE CO2 A COMBUSTIBLES Y COMPUESTOS DE ALTO VALOR AÑADIDO MEDIANTE CATALISIS HOMOGENEA Y NANO-CATALISIS
Publication Type: Journal Publications
Repositori URV