Author, as appears in the article.: Viguiliouk, Effie; Glenn, Andrea J.; Nishi, Stephanie K.; Chiavaroli, Laura; Seider, Maxine; Khan, Tauseef; Bonaccio, Marialaura; Lacoviello, Licia; Mejia, Sonia Blanco; Jenkins, David J. A.; Kendall, Cyril W. C.; Kahleova, Hana; Rahelic, Dario; Salas-Salvado, Jordi; Sievenpiper, John L.;

Department: Bioquímica i Biotecnologia

URV's Author/s: Salas Salvadó, Jorge

Keywords: Systematic review Pulses Protein sources Prospective cohort Processed meat Obesity Meta-analysis Mediterranean diet Legumes Hypertension Grade Glycemic index Food groups Findings tables Diabetes Coronary-heart-disease Cause-specific mortality Cardiovascular-disease Cardiovascular disease Atherosclerosis risk pulses prospective cohort obesity meta-analysis legumes hypertension grade diabetes cardiovascular disease

Abstract: To update the European Association for the Study of Diabetes clinical practice guidelines for nutrition therapy, we conducted an umbrella review and updated systematic review and meta-analysis (SRMA) of prospective cohort studies of the association between dietary pulses with or without other legumes and cardiometabolic disease outcomes. We searched the PubMed, MEDLINE, EMBASE, and Cochrane databases through March 2019. We included the most recent SRMAs of prospective cohort studies and new prospective cohort studies published after the census dates of the included SRMAs assessing the relation between dietary pulses with or without other legumes and incidence and mortality of cardiovascular diseases (CVDs) [including coronary heart disease (CHD), myocardial infarction (MI), and stroke], diabetes, hypertension, and/or obesity. Two independent reviewers extracted data and assessed risk of bias. Risk estimates were pooled using the generic inverse variance method and expressed as risk ratios (RRs) with 95% CIs. The overall certainty of the evidence was assessed using the GRADE approach. Six SRMAs were identified and updated to include 28 unique prospective cohort studies with the following number of cases for each outcome: CVD incidence, 10,261; CVD mortality, 16,168; CHD incidence, 7786; CHD mortality, 3331; MI incidence, 2585; stroke incidence, 8570; stroke mortality, 2384; diabetes incidence, 10,457; hypertension incidence, 83,284; obesity incidence, 8125. Comparing the highest with the lowest level of intake, dietary pulses with or without other legumes were associated with significant decreases in CVD (RR: 0.92; 95% CI: 0.85, 0.99), CHD (RR: 0.90; 95% CI: 0.83, 0.99), hypertension (RR: 0.91; 95% CI: 0.86, 0.97), and obesity (RR: 0.87; 95% CI: 0.81, 0.94) incidence. There was no association with MI, stroke, and diabetes incidence or CVD, CHD, and stroke mortality. The overall certainty of the evidence was graded as low for CVD incidence and very low for all other outcomes. Current evidence shows that dietary pulses with or without other legumes are associated with reduced CVD incidence with low certainty and reduced CHD, hypertension, and obesity incidence with very low certainty. More research is needed to improve our estimates.

Thematic Areas: Saúde coletiva Nutrition and dietetics Nutrition & dietetics Nutrição Medicine (miscellaneous) Medicina ii Food science Educação física Ciências biológicas ii Ciências biológicas i Ciência de alimentos

licence for use: https://creativecommons.org/licenses/by/3.0/es/

ISSN: 21565376

Author's mail: jordi.salas@urv.cat

Author identifier: 0000-0003-2700-7459

Record's date: 2023-02-18

Papper version: info:eu-repo/semantics/publishedVersion

Link to the original source: https://academic.oup.com/advances/article/10/Supplement_4/S308/5624066

Licence document URL: http://repositori.urv.cat/ca/proteccio-de-dades/

Papper original source: Advances In Nutrition. 10 (S4): S308-S319

APA: Viguiliouk, Effie; Glenn, Andrea J.; Nishi, Stephanie K.; Chiavaroli, Laura; Seider, Maxine; Khan, Tauseef; Bonaccio, Marialaura; Lacoviello, Licia; M (2019). Associations between Dietary Pulses Alone or with Other Legumes and Cardiometabolic Disease Outcomes: An Umbrella Review and Updated Systematic Review and Meta-analysis of Prospective Cohort Studies.

Article's DOI: 10.1093/advances/nmz113

Entity: Universitat Rovira i Virgili

Journal publication year: 2019

Publication Type: Proceedings Paper