Author, as appears in the article.: Arija V; Hernández-Martínez C; Tous M; Canals J; Guxens M; Fernández-Barrés S; Ibarluzea J; Babarro I; Soler-Blasco R; Llop S; Vioque J; Sunyer J; Julvez J
Department: Ciències Mèdiques Bàsiques
URV's Author/s: Arija Val, Maria Victoria / Canals Sans, Josefa / Hernandez Martinez, Carmen / TOUS MÁRQUEZ, MÒNICA
Keywords: Working-memory Working memory Women Psychomotor development Pregnancy Newborn-infants Neuropsychological function Micronutrient supplementation Iron status Iron intake Follow-up Explicit memory performance Executive function Deficiency alters Cognition Auditory recognition memory Attention pregnancy neuropsychological function iron status iron intake executive function attention
Abstract: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. Early iron status plays an important role in prenatal neurodevelopment. Iron deficiency and high iron status have been related to alterations in child cognitive development; however, there are no data about iron intake during pregnancy with other environmental factors in relation to long term cognitive functioning of children. The aim of this study is to assess the relationship between maternal iron status and iron intake during pregnancy and child neuropsychological outcomes at 7 years of age. We used data from the INMA Cohort population-based study. Iron status during pregnancy was assessed according to serum ferritin levels, and iron intake was assessed with food frequency questionnaires. Working memory, attention, and executive function were assessed in children at 7 years old with the N-Back task, Attention Network Task, and the Trail Making Test, respectively. The results show that, after controlling for potential confounders, normal maternal serum ferritin levels (from 12 mg/L to 60 mg/L) and iron intake (from 14.5 mg/day to 30.0 mg/day), respectively, were related to better scores in working memory and executive functioning in offspring. Since these functions have been associated with better academic performance and adaptation to the environment, maintaining a good state of maternal iron from the beginning of pregnancy could be a valuable strategy for the community.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20726643
Author's mail: victoria.arija@urv.cat josefa.canals@urv.cat carmen.hernandez@urv.cat
Author identifier: 0000-0002-1758-0975 0000-0002-6209-9558 0000-0001-6328-8679
Record's date: 2023-02-18
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2072-6643/11/12/2999
Papper original source: Nutrients. 11 (12):
APA: Arija V; Hernández-Martínez C; Tous M; Canals J; Guxens M; Fernández-Barrés S; Ibarluzea J; Babarro I; Soler-Blasco R; Llop S; Vioque J; Sunyer J; Jul (2019). Association of iron status and intake during pregnancy with neuropsychological outcomes in children aged 7 years: The prospective birth cohort infancia y medio ambiente (INMA) study. Nutrients, 11(12), -. DOI: 10.3390/nu11122999
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Article's DOI: 10.3390/nu11122999
Entity: Universitat Rovira i Virgili
Journal publication year: 2019
Publication Type: Journal Publications
Repositori URV