Author, as appears in the article.: Pfeiffer, Andreas F H; Pedersen, Eva; Schwab, Ursula; Riserus, Ulf; Aas, Anne-Marie; Uusitupa, Matti; Thanopoulou, Anastasia; Kendall, Cyril; Sievenpiper, John L; Kahleova, Hana; Rahelic, Dario; Salas-Salvado, Jordi; Gebauer, Stephanie; Hermansen, Kjeld
Department: Bioquímica i Biotecnologia
URV's Author/s: Salas Salvadó, Jorge
Keywords: Weight-loss Weight loss Type-2 Type 2 diabetes Randomized controlled-trial Protein intake Plant protein Middle aged Metaanalysis Management Male Low-fat diet Individuals Hypocaloric diet Humans Hemoglobin a1c protein, human Glycated hemoglobin a Glycated hemoglobin Glomerular filtration rate Female Energy intake Dietary proteins Dietary carbohydrate-restriction Diet, protein-restricted Diet, high-protein Diabetes mellitus, type 2 Body-weight Blood-pressure Blood pressure Animal protein Adult type 2 diabetes protein intake plant protein hypocaloric diet animal protein
Abstract: © 2020 by the authors. Licensee MDPI, Basel, Switzerland. The recommended amount and quality of protein in diets of diabetic patients are highly controversial. In order to provide evidence-based information, the Diabetes Nutrition Study Group (DNSG) used a grading procedure used for quality of evidence and strength of recommendations (GRADE). A protein intake of 10% to 20% of energy intake (E%) or about 0.8 to 1.3 g/kg body weight in people below 65 years of age, and 15% to 20% of E% in people above 65 years of age appeared safe in weight-stable conditions. There were no intervention studies addressing metabolic effects, mortality, or cardiovascular events over prolonged periods. Body weight is closely linked to metabolic control and high protein diets are often recommended. Weight-loss diets that include 23% to 32% of E% as protein for up to one year reduced blood pressure and body weight slightly but significantly more than lower protein diets, whereas blood lipids, fasting blood glucose, and HbA1c improved similarly with higher or lower protein intakes in participants with a glomerular filtration rate (GFR) >60 mL/min/1.73 m2 . Patients with a GFR <60 mL/min/1.73 m2 did not show a faster decline of GFR or kidney function with protein intakes around 0.8 g/kg body weight as compared with lower intakes, thereby arguing against a restriction. The effects of protein intake on diabetic eye or nerve disease have not been reported. There are a number of studies that have compared different types of animal proteins (milk, chicken, beef, pork, and fish) or compared animal with plant protein in diabetic patients and have reported a greater reduction of serum cholesterol with plant protein. In summary, the suggested range of protein intake appears to be safe and can be adapted according to personal dietary preferences.
Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Planejamento urbano e regional / demografia Nutrition and dietetics Nutrition & dietetics Nutrição Medicina veterinaria Medicina iii Medicina ii Medicina i Interdisciplinar Food science Farmacia Engenharias iv Engenharias ii Enfermagem Educação física Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología
licence for use: https://creativecommons.org/licenses/by/3.0/es/
ISSN: 20726643
Author's mail: jordi.salas@urv.cat
Author identifier: 0000-0003-2700-7459
Record's date: 2025-02-18
Paper version: info:eu-repo/semantics/publishedVersion
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Paper original source: Nutrients. 12 (2): 365-
APA: Pfeiffer, Andreas F H; Pedersen, Eva; Schwab, Ursula; Riserus, Ulf; Aas, Anne-Marie; Uusitupa, Matti; Thanopoulou, Anastasia; Kendall, Cyril; Sievenpi (2020). The effects of different quantities and qualities of protein intake in people with diabetes mellitus. Nutrients, 12(2), 365-. DOI: 10.3390/nu12020365
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications
Repositori URV