Repositori URV

Identifier: imarina:6124593

Handle: https://hdl.handle.net/20.500.11797/imarina6124593

Authors:
Fernandez-Garcia, Jose CarlosMunoz-Garach, AraceliMartinez-Gonzalez, Miguel angelSalas-Salvado, JordiCorella, DoloresHernaez, AlvaroRomaguera, DoraVioque, JesusAlonso-Gomez, Angel M.Warnberg, JuliaMartinez, J. AlfredoSerra-Majem, LuisEstruch, RamonLapetra, JosePinto, XavierTur, Josep A.Garcia-Rios, AntonioGarcia Molina, LauraGaforio, Jose JuanMatia-Martin, PilarDaimiel, LidiaMartin Sanchez, VicenteVidal, JosepPrieto, LuciaRos, EmilioGoni, NuriaBabio, NancyOrtega-Azorin, CarolinaCastaner, OlgaKonieczna, JadwigaNotario Barandiaran, LeyreVaquero-Luna, JessicaBenavente-Marin, Juan CarlosZulet, M. AngelesSanchez-Villegas, AlmudenaSacanella, EmilioGomez Huelgas, RicardoMiro-Moriano, LeticiaGimenez-Gracia, MarianoJulibert, AliciaRazquin, CristinaBasora, JosepPortoles, OlgaGoday, AlbertGalmes-Panades, Aina M.Lopez-Garcia, Carmen M.Moreno-Rodriguez, AnaiToledo, EstefaniaDiaz-Lopez, AndresFito, MontserratTinahones, Francisco J.Bernal-Lopez, M. RosaPREDIMED-Plus Investigators

Abstract:
Objective The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross-sectional assessment of PREDIMED-Plus trial participants at baseline, HTGW phenotype prevalence was evaluated, associated risk factors were analyzed, and the lifestyle of individuals with metabolic syndrome and HTGW was examined. Methods A total of 6,874 individuals aged 55 to 75 with BMI >= 27 and < 40 kg/m(2) were included and classified by presence (HTGW(+)) or absence (HTGW(-)) of HTGW (waist circumference: men >= 102 cm, women >= 88 cm; fasting plasma triglycerides >= 150 mg/dL). Analytical parameters and lifestyle (energy intake and expenditure) were analyzed. Results A total of 38.2% of the sample met HTGW(+) criteria. HTGW(+) individuals tended to be younger, have a greater degree of obesity, be sedentary, and be tobacco users. They had higher peripheral glucose, total cholesterol, and low-density lipoprotein cholesterol levels; had lower high-density lipoprotein cholesterol levels; and had increased prevalence of type 2 diabetes mellitus. Mediterranean diet (MedDiet) adherence and physical activity were greater in HTGW(-) patients. Age, BMI, tobacco use, total energy expenditure, hypertension, type 2 diabetes mellitus, and MedDiet adherence were associated with HTGW(+). Conclusions HTGW is a highly prevalent phenotype in this population associated with younger age, higher BMI, tobacco use, and decreased MedDiet adherence. HTGW(-) individuals were more physically active with greater total physical activity, and fewer had hypertension.