Buchwald-Type Ligands on Gold(I) Catalysis

Identifier:  imarina:6138918

Handle: https://hdl.handle.net/20.500.11797/imarina6138918

Authors:  Zuccarello, G; Zanini, M; Echavarren, AM

Abstract:
Dialkyl biarylphosphine ligands, presented in the context of Pd-catalyzed cross-coupling reactions, have been extensively applied in gold(I) catalysis giving rise to numerous transformations and reaction pathways otherwise inaccessible under the action of other gold(I) catalysts. This review emphasizes how this privileged ligand class, as well as recent modifications on the biarylphosphine motive, have triggered the discovery of new reactivities in our research program. Finally, the introduction of chiral information on the ligand scaffold provides new solutions to challenging gold(I)-catalyzed enantioselective transformations.