Articles producció científica> Antropologia, Filosofia i Treball Social

Effects of ayahuasca on mental health and quality of life in naïve users: A longitudinal and cross-sectional study combination

  • Identification data

    Identifier: imarina:6173699
    Authors:
    Jiménez-Garrido D.F., Gómez-Sousa M., Ona G., Dos Santos R.G., Hallak J.E.C., Alcázar-Córcoles M.Á., Bouso J.C.
    Abstract:
    © 2020, The Author(s). Ayahuasca is a hallucinogenic decoction used as a traditional medicine in several Amazonian regions. The ritualistic use of ayahuasca has spread throughout many countries, making it necessary to study its risks and benefits. Two sub-studies were designed for this investigation. In sub-study 1, a psychiatric interview and a battery of questionnaires were administered to subjects (n = 40) before their first ayahuasca use. Two follow-ups were conducted at 1 and 6 months. In sub-study 2, the same interview and battery of questionnaires were administered to long-term ayahuasca users (n = 23) and their scores were compared with those of the ayahuasca-naïve group. In the first assessment, nearly half (45%) of the naïve users were found to meet the diagnostic criteria for a psychiatric disorder. After the ayahuasca use, more than 80% of those subjects showed clinical improvements that persisted at 6 months. The questionnaires showed significant reductions in depression and psychopathology. Regarding sub-study 2, long-term users showed lower depression scores, and higher scores for self-transcendence and quality of life, as compared to their peers in sub-study 1. Further controlled and observational naturalistic studies assessing the eventual risks and potential benefits of ayahuasca are warranted.
  • Others:

    Author, as appears in the article.: Jiménez-Garrido D.F., Gómez-Sousa M., Ona G., Dos Santos R.G., Hallak J.E.C., Alcázar-Córcoles M.Á., Bouso J.C.
    Department: Antropologia, Filosofia i Treball Social
    URV's Author/s: Oña Esteve, Genís
    Keywords: Validation Spanish version Religion Recurrent depression Psychological inflexibility Personality Experiences Context Action questionnaire Acceptance
    Abstract: © 2020, The Author(s). Ayahuasca is a hallucinogenic decoction used as a traditional medicine in several Amazonian regions. The ritualistic use of ayahuasca has spread throughout many countries, making it necessary to study its risks and benefits. Two sub-studies were designed for this investigation. In sub-study 1, a psychiatric interview and a battery of questionnaires were administered to subjects (n = 40) before their first ayahuasca use. Two follow-ups were conducted at 1 and 6 months. In sub-study 2, the same interview and battery of questionnaires were administered to long-term ayahuasca users (n = 23) and their scores were compared with those of the ayahuasca-naïve group. In the first assessment, nearly half (45%) of the naïve users were found to meet the diagnostic criteria for a psychiatric disorder. After the ayahuasca use, more than 80% of those subjects showed clinical improvements that persisted at 6 months. The questionnaires showed significant reductions in depression and psychopathology. Regarding sub-study 2, long-term users showed lower depression scores, and higher scores for self-transcendence and quality of life, as compared to their peers in sub-study 1. Further controlled and observational naturalistic studies assessing the eventual risks and potential benefits of ayahuasca are warranted.
    Thematic Areas: Zootecnia / recursos pesqueiros Saúde coletiva Química Psicología Odontología Nutrição Multidisciplinary sciences Multidisciplinary Medicina veterinaria Medicina iii Medicina ii Medicina i Materiais Matemática / probabilidade e estatística Letras / linguística Interdisciplinar Geografía Geociências Farmacia Engenharias iv Engenharias iii Engenharias ii Enfermagem Educação física Educação Economia Ciências biológicas iii Ciências biológicas ii Ciências biológicas i Ciências ambientais Ciências agrárias i Ciência de alimentos Ciência da computação Biotecnología Biodiversidade Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    Author's mail: genis.ona@urv.cat genis.ona@urv.cat
    Record's date: 2022-10-08
    Papper version: info:eu-repo/semantics/publishedVersion
    Link to the original source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057990/
    Papper original source: Scientific Reports. 10 (1): 4075-
    APA: Jiménez-Garrido D.F., Gómez-Sousa M., Ona G., Dos Santos R.G., Hallak J.E.C., Alcázar-Córcoles M.Á., Bouso J.C. (2020). Effects of ayahuasca on mental health and quality of life in naïve users: A longitudinal and cross-sectional study combination. Scientific Reports, 10(1), 4075-. DOI: 10.1038/s41598-020-61169-x
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1038/s41598-020-61169-x
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2020
    Publication Type: Journal Publications
  • Keywords:

    Multidisciplinary,Multidisciplinary Sciences
    Validation
    Spanish version
    Religion
    Recurrent depression
    Psychological inflexibility
    Personality
    Experiences
    Context
    Action questionnaire
    Acceptance
    Zootecnia / recursos pesqueiros
    Saúde coletiva
    Química
    Psicología
    Odontología
    Nutrição
    Multidisciplinary sciences
    Multidisciplinary
    Medicina veterinaria
    Medicina iii
    Medicina ii
    Medicina i
    Materiais
    Matemática / probabilidade e estatística
    Letras / linguística
    Interdisciplinar
    Geografía
    Geociências
    Farmacia
    Engenharias iv
    Engenharias iii
    Engenharias ii
    Enfermagem
    Educação física
    Educação
    Economia
    Ciências biológicas iii
    Ciências biológicas ii
    Ciências biológicas i
    Ciências ambientais
    Ciências agrárias i
    Ciência de alimentos
    Ciência da computação
    Biotecnología
    Biodiversidade
    Astronomia / física
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