Author, as appears in the article.: de Hollanda, Ana; Lecube, Albert; Angel Rubio, Miguel; Sanchez, Enric; Vilarrasa, Nuria; Gregorio Oliva, Jose; Luisa Fernandez-Soto, Maria; Salas-Salvado, Jordi; Ballesteros-Pomar, Maria D.; Ciudin, Andreea; Torres, Ferran; Vidal, Concepcion; Jose Morales, Maria; Valdes, Sergio; Pellitero, Silvia; Minambres, Inka; Masmiquel, Lluis; Goday, Albert; Suarez, Lorena; Flores, Liliam; Bueno, Marta; Caixas, Assumpta; Breton, Irene; Camara, Rosa; Olbeyra, Romina; Penso, Rona; Jose de la Cruz, Maria; Simo-Servat, Andreu; Maria Pereyra-Garcia, Francisca; Teresa Lopez-Mezquita, Elena; Gils, Anna; Fidilio, Enzamaria; Bandres, Orosia; Martinez, Angel; Abuin, Jose; Marques-Pamies, Montserrat; Tuneu, Laura; Arteaga, Magdalena; Castaner, Olga; Goni, Fernando; Arrizabalaga, Cristina; Antonio Botana, Manuel; Calanas, Alfonso; Rebollo, Angel;
Department: Bioquímica i Biotecnologia
URV's Author/s: Salas Salvadó, Jorge
Keywords: Y-gastric bypass Weight-loss Type 2 diabetes Time-within-remission range Propensity score methods Obesity Metabolic surgery Metabolic control Laparoscopic sleeve gastrectomy Follow-up Bariatric surgery time-within-remission range metabolic control bariatric surgery
Abstract: Almost one third of patients do not achieve type 2 diabetes remission after bariatric surgery or are unable to sustain this effect long term. Our objective was to delve further into the dynamic responses of diabetes after bariatric surgery and to evaluate the time-within-remission range as a variable of metabolic control. A descriptive cohort study was done using a computerised multicentre and multidisciplinary registry. All data were adjusted by propensity score. A total of 1186 subjects with a follow-up of 4.5 +/- 2.5 years were included. Type of surgery, diabetes remission, recurrence of diabetes, time-within-remission range and key predictors of diabetes outcomes were assessed. All patients (70% women, 51.4 +/- 9.2 years old, body mass index (BMI) 46.3 +/- 6.9 kg/m(2)) underwent primary bariatric procedures. Time-within-remission range were 83.3% (33.3-91.6) after gastric bypass, 68.7% (7.1-87.5) after sleeve gastrectomy and 90% (83.3-92.8) after malabsorptive techniques (p < 0.001 for all). Duration of diabetes, baseline HbA1c and insulin treatment were significantly negatively correlated with the time-within-remission range. The association of bariatric techniques with time-within-remission range, using gastric bypass as a reference, were: odds ratio (OR) 3.70 (2.34-5.84), p < 0.001 for malabsorptive techniques and OR 0.55 (0.40-0.75), p < 0.001 for sleeve gastrectomy. Characteristics of type 2 diabetes powerfully influence the outcomes of bariatric surgery. The time-within-remission range unveils a superiority of gastric bypass compared to sleeve gastrectomy.
Thematic Areas: Medicine, general & internal Medicine (miscellaneous) Medicine (all)
licence for use: https://creativecommons.org/licenses/by/3.0/es/
Author's mail: jordi.salas@urv.cat
Author identifier: 0000-0003-2700-7459
Record's date: 2024-09-07
Papper version: info:eu-repo/semantics/publishedVersion
Link to the original source: https://www.mdpi.com/2077-0383/9/4/1070
Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
Papper original source: Journal Of Clinical Medicine. 9 (4):
APA: de Hollanda, Ana; Lecube, Albert; Angel Rubio, Miguel; Sanchez, Enric; Vilarrasa, Nuria; Gregorio Oliva, Jose; Luisa Fernandez-Soto, Maria; Salas-Salv (2020). New Metrics to Assess Type 2 Diabetes after Bariatric Surgery: The Time-Within-Remission Range. Journal Of Clinical Medicine, 9(4), -. DOI: 10.3390/jcm9041070
Article's DOI: 10.3390/jcm9041070
Entity: Universitat Rovira i Virgili
Journal publication year: 2020
Publication Type: Journal Publications
Repositori URV