Articles producció científica> Bioquímica i Biotecnologia

miRNAs, polyphenols, and chronic disease

  • Identification data

    Identifier: imarina:6387220
    Handle: https://hdl.handle.net/20.500.11797/imarina6387220
    Authors:
    Bladé CBaselga-Escudero LSalvadó MArola-Arnal A
    Abstract:
    MicroRNAs (miRNAs) are small noncoding RNAs, approximately 18-25 nucleotides in length, that modulate gene expression at the posttranscriptional level. Thousands of miRNAs have been described, and it is thought that they regulate some aspects of more than 60% of all human cell transcripts. Several polyphenols have been shown to modulate miRNAs related to metabolic homeostasis and chronic diseases. Polyphenolic modulation of miRNAs is very attractive as a strategy to target numerous cell processes and potentially reduce the risk of chronic disease. Evidence is building that polyphenols can target specific miRNAs, such as miR-122, but more studies are necessary to discover and validate additional miRNA targets. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  • Others:

    Author, as appears in the article.: Bladé C; Baselga-Escudero L; Salvadó M; Arola-Arnal A
    Department: Bioquímica i Biotecnologia
    URV's Author/s: Arola Arnal, Anna / BASELGA ESCUDERO, LAURA / BLADÉ SEGARRA, MARIA CINTA / Salvadó Rovira, Maria Josepa
    Keywords: Polyphenols Microrna Lipid metabolism Insulin Cardiovascular
    Abstract: MicroRNAs (miRNAs) are small noncoding RNAs, approximately 18-25 nucleotides in length, that modulate gene expression at the posttranscriptional level. Thousands of miRNAs have been described, and it is thought that they regulate some aspects of more than 60% of all human cell transcripts. Several polyphenols have been shown to modulate miRNAs related to metabolic homeostasis and chronic diseases. Polyphenolic modulation of miRNAs is very attractive as a strategy to target numerous cell processes and potentially reduce the risk of chronic disease. Evidence is building that polyphenols can target specific miRNAs, such as miR-122, but more studies are necessary to discover and validate additional miRNA targets. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
    Thematic Areas: Saúde coletiva Química Nutrição Medicina veterinaria Medicina ii Medicina i Interdisciplinar Food science & technology Food science Farmacia Educação física Ciências biológicas ii Ciências biológicas i Ciências agrárias i Ciência de alimentos Biotecnología Biotechnology Astronomia / física
    licence for use: https://creativecommons.org/licenses/by/3.0/es/
    ISSN: 16134125
    Author's mail: mariajosepa.salvado@urv.cat anna.arola@urv.cat
    Author identifier: 0000-0003-3883-3326 0000-0001-6529-1345
    Record's date: 2023-02-19
    Papper version: info:eu-repo/semantics/submittedVersion
    Link to the original source: https://onlinelibrary.wiley.com/doi/abs/10.1002/mnfr.201200454
    Papper original source: Molecular Nutrition & Food Research. 57 (1): 58-70
    APA: Bladé C; Baselga-Escudero L; Salvadó M; Arola-Arnal A (2013). miRNAs, polyphenols, and chronic disease. Molecular Nutrition & Food Research, 57(1), 58-70. DOI: 10.1002/mnfr.201200454
    Licence document URL: https://repositori.urv.cat/ca/proteccio-de-dades/
    Article's DOI: 10.1002/mnfr.201200454
    Entity: Universitat Rovira i Virgili
    Journal publication year: 2013
    Publication Type: Journal Publications

  • Keywords:

    Biotechnology,Food Science,Food Science & Technology
    Polyphenols
    Microrna
    Lipid metabolism
    Insulin
    Cardiovascular
    Saúde coletiva
    Química
    Nutrição
    Medicina veterinaria
    Medicina ii
    Medicina i
    Interdisciplinar
    Food science & technology
    Food science
    Farmacia
    Educação física
    Ciências biológicas ii
    Ciências biológicas i
    Ciências agrárias i
    Ciência de alimentos
    Biotecnología
    Biotechnology
    Astronomia / física

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